Psychedelic-assisted therapy for palliative care within a home treatment setting: A case report.
Seragnoli FedericoMartignoni GeoMartignoni EntelaSilke BachmannRabitti ElisaSilvio CavutoDubus ZoëPenzenstadler LouiseThorens GabrielBillieux JoëlZullino DanielePublished in: Clinical case reports (2024)
Psychedelic-assisted therapy (PAT), as it is practiced today, merges traditional psychotherapeutic techniques with the use of psychedelics such as LSD, psilocybin, or MDMA with the aim of unlocking deeper insights in patients and treating mental conditions that are resistant to other forms of therapy. The present case study describes the safety of PAT as a home-based intervention for a patient with throat cancer experiencing significant existential distress. The patient tolerated the intervention well and was asked to report on measures of anxiety, depression, and distress related to his somatic condition. The observations provided by this clinical case report align with previous findings, suggesting that PAT can be safely applied to potentially provide relief from existential distress in patients with life-threatening conditions. As this is a single-case study, generalizations should be made cautiously. Moreover, placebo effects, expectancy effects, and the natural course of the disease may influence outcomes. Future research should consider controlled trials to ascertain the efficacy and safety of such interventions in diverse settings.
Keyphrases
- case report
- palliative care
- randomized controlled trial
- end stage renal disease
- newly diagnosed
- physical activity
- sleep quality
- depressive symptoms
- prognostic factors
- stem cells
- clinical trial
- peritoneal dialysis
- papillary thyroid
- mental health
- dna methylation
- gene expression
- advanced cancer
- adipose tissue
- metabolic syndrome
- mesenchymal stem cells
- bone marrow
- study protocol
- weight loss
- open label
- drug induced
- smoking cessation