Energy metabolism of white adipose tissue and insulin resistance in humans.

Published in: European journal of clinical investigation (2018)

Abnormal mitochondrial function in human white adipose tissue likely contributes to the secretion of lipid metabolites and lactate, which are linked to insulin resistance in peripheral tissues. However, the relevance of adipose tissue energy metabolism for the regulation of human insulin sensitivity remains to be further elucidated.

Keyphrases

adipose tissue
endothelial cells
insulin resistance
high fat diet
induced pluripotent stem cells
pluripotent stem cells
gene expression
ms ms
type diabetes
fatty acid