Quinoline-based compounds can inhibit diverse enzymes that act on DNA.
Jujun ZhouQin ChenRen RenJie YangBigang LiuJohn R HortonCaleb ChangChuxuan LiLeora MaksoudYifei YangDante RotiliXing ZhangRobert M BlumenthalJiameng DanYang GaoSergio ValenteAntonello MaiXiaodong ChengPublished in: bioRxiv : the preprint server for biology (2024)
provokes DNA damage response via p53 activation in cancer cells.