Dante Rotili

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 78

Top Topics

Trypanosoma Cruzi

Cancer Stem Cells

Oxidative Stress

Histone Deacetylase

Top Venues

Journal of medicinal chemistry

Journal of enzyme inhibition and medicinal chemistry

ACS chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Martin Pannek, Zayan Alhalabi, Daniela Tomaselli, Martina Menna, Francesco Fiorentino, Dina Robaa, Michael Weyand, Maximilian Puhlmann, Stefano Tomassi, Federica Barreca, Marco Tafani, Elma Zaganjor, Marcia C Haigis, Wolfgang Sippl, Dante Rotili, Antonello Mai, Clemens Steegborn
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity. Journal of medicinal chemistry 67 (3) (2024)
Angela Iuzzolino, Francesca Romana Pellegrini, Dante Rotili, Francesca Degrassi, Daniela Trisciuoglio
The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Angela Iuzzolino, Francesca Romana Pellegrini, Dante Rotili, Francesca Degrassi, Daniela Trisciuoglio
The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Angela Iuzzolino, Francesca Romana Pellegrini, Dante Rotili, Francesca Degrassi, Daniela Trisciuoglio
The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Antonello Mai, Dante Rotili
Activation and inhibition of sirtuins: From bench to bedside. Medicinal research reviews (2024)
Federico Appetecchia, Emanuele Fabbrizi, Francesco Fiorentino, Sara Consalvi, Mariangela Biava, Giovanna Poce, Dante Rotili
Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development. Pharmaceuticals (Basel, Switzerland) 17 (7) (2024)
Monica Viviano, Alessandra Cipriano, Emanuele Fabbrizi, Alessandra Feoli, Sabrina Castellano, Gianluca Sbardella, Antonello Mai, Ciro Milite, Dante Rotili
Successes and challenges in the development of BD1-selective BET inhibitors: a patent review. Expert opinion on therapeutic patents 34 (7) (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Alessia Raucci, Beatrice Noce, Rossella Fioravanti, Sergio Valente, Chantal Paolini, Ruggero De Maria, Christian Steinkühler, Paola Gallinari, Dante Rotili, Antonello Mai
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells. ChemMedChem 19 (13) (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Alessia Raucci, Beatrice Noce, Rossella Fioravanti, Sergio Valente, Chantal Paolini, Ruggero De Maria, Christian Steinkühler, Paola Gallinari, Dante Rotili, Antonello Mai
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells. ChemMedChem 19 (13) (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Alessia Raucci, Beatrice Noce, Rossella Fioravanti, Sergio Valente, Chantal Paolini, Ruggero De Maria, Christian Steinkühler, Paola Gallinari, Dante Rotili, Antonello Mai
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells. ChemMedChem (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Alessia Raucci, Beatrice Noce, Rossella Fioravanti, Sergio Valente, Chantal Paolini, Ruggero De Maria, Christian Steinkühler, Paola Gallinari, Dante Rotili, Antonello Mai
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells. ChemMedChem 19 (13) (2024)
Federico Appetecchia, Emanuele Fabbrizi, Francesco Fiorentino, Sara Consalvi, Mariangela Biava, Giovanna Poce, Dante Rotili
Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development. Pharmaceuticals (Basel, Switzerland) 17 (7) (2024)
Jujun Zhou, Qin Chen, Ren Ren, Jie Yang, Bigang Liu, John R Horton, Caleb Chang, Chuxuan Li, Leora Maksoud, Yifei Yang, Dante Rotili, Xing Zhang, Robert M Blumenthal, Jiameng Dan, Yang Gao, Sergio Valente, Antonello Mai, Xiaodong Cheng
Quinoline-based compounds can inhibit diverse enzymes that act on DNA. bioRxiv : the preprint server for biology (2024)
Monica Viviano, Alessandra Cipriano, Emanuele Fabbrizi, Alessandra Feoli, Sabrina Castellano, Gianluca Sbardella, Antonello Mai, Ciro Milite, Dante Rotili
Successes and challenges in the development of BD1-selective BET inhibitors: a patent review. Expert opinion on therapeutic patents (2024)
Anastasia Golovina, Eleonora Proia, Francesco Fiorentino, Maxim A Yunin, Maria Kasatkina, Nailya Zigangirova, Anna Soloveva, Elena Sysolyatina, Svetlana Ermolaeva, Roman A Novikov, Sergei Silonov, Sergei Pushkin, Milan Mladenović, Julia Isakova, Albina Belik, Maxim Nawrozkij, Dante Rotili, Rino Ragno, Roman Ivanov
(Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling. ACS infectious diseases (2024)
Federico Appetecchia, Emanuele Fabbrizi, Francesco Fiorentino, Sara Consalvi, Mariangela Biava, Giovanna Poce, Dante Rotili
Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development. Pharmaceuticals (Basel, Switzerland) 17 (7) (2024)
Monica Viviano, Alessandra Cipriano, Emanuele Fabbrizi, Alessandra Feoli, Sabrina Castellano, Gianluca Sbardella, Antonello Mai, Ciro Milite, Dante Rotili
Successes and challenges in the development of BD1-selective BET inhibitors: a patent review. Expert opinion on therapeutic patents 34 (7) (2024)
Martin Pannek, Zayan Alhalabi, Daniela Tomaselli, Martina Menna, Francesco Fiorentino, Dina Robaa, Michael Weyand, Maximilian Puhlmann, Stefano Tomassi, Federica Barreca, Marco Tafani, Elma Zaganjor, Marcia C Haigis, Wolfgang Sippl, Dante Rotili, Antonello Mai, Clemens Steegborn
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity. Journal of medicinal chemistry (2024)
Angela Iuzzolino, Francesca Romana Pellegrini, Dante Rotili, Francesca Degrassi, Daniela Trisciuoglio
The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Martin Pannek, Zayan Alhalabi, Daniela Tomaselli, Martina Menna, Francesco Fiorentino, Dina Robaa, Michael Weyand, Maximilian Puhlmann, Stefano Tomassi, Federica Barreca, Marco Tafani, Elma Zaganjor, Marcia C Haigis, Wolfgang Sippl, Dante Rotili, Antonello Mai, Clemens Steegborn
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity. Journal of medicinal chemistry 67 (3) (2024)
Anastasia Golovina, Eleonora Proia, Francesco Fiorentino, Maxim A Yunin, Maria Kasatkina, Nailya Zigangirova, Anna Soloveva, Elena Sysolyatina, Svetlana Ermolaeva, Roman A Novikov, Sergei Silonov, Sergei Pushkin, Milan Mladenović, Julia Isakova, Albina Belik, Maxim Nawrozkij, Dante Rotili, Rino Ragno, Roman Ivanov
(Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling. ACS infectious diseases 10 (6) (2024)
Francesco Fiorentino, Alessio Nocentini, Dante Rotili, Claudiu T Supuran, Antonello Mai
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Francesco Fiorentino, Sara Sementilli, Martina Menna, Federica Turrisi, Stefano Tomassi, Francesca Romana Pellegrini, Angela Iuzzolino, Francesca D'Acunzo, Alessandra Feoli, Hannah Wapenaar, Sophie Taraglio, Caterina Fraschetti, Donatella Del Bufalo, Gianluca Sbardella, Frank J Dekker, Alessandro Paiardini, Daniela Trisciuoglio, Antonello Mai, Dante Rotili
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8. Journal of medicinal chemistry (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Emanuele Fabbrizi, Francesco Fiorentino, Vincenzo Carafa, Lucia Altucci, Antonello Mai, Dante Rotili
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection. Cells 12 (6) (2023)
Michele Aventaggiato, Federica Barreca, Laura Vitiello, Simone Vespa, Sergio Valente, Dante Rotili, Antonello Mai, Lavinia Vittoria Lotti, Luigi Sansone, Matteo Antonio Russo, Mariano Bizzarri, Elisabetta Ferretti, Marco Tafani
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery. Cells 12 (5) (2023)
Aide Negri, Marina Marozzi, Daniela Trisciuoglio, Dante Rotili, Antonello Mai, Federica Rizzi
Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Vanessa Marchant, Flavia Trionfetti, Lucia Tejedor-Santamaria, Sandra Rayego-Mateos, Dante Rotili, Giulio Bontempi, Alessandro Domenici, Paolo Menè, Antonello Mai, Catalina Martín-Cleary, Alberto Ortiz Arduan, Adrian M Ramos, Raffaele Strippoli, Marta Ruiz-Ortega
BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress. Antioxidants (Basel, Switzerland) 12 (12) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Michele Aventaggiato, Federica Barreca, Laura Vitiello, Simone Vespa, Sergio Valente, Dante Rotili, Antonello Mai, Lavinia Vittoria Lotti, Luigi Sansone, Matteo Antonio Russo, Mariano Bizzarri, Elisabetta Ferretti, Marco Tafani
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery. Cells 12 (5) (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Francesco Fiorentino, Fabrizio Carta, Dante Rotili, Antonello Mai, Claudiu T Supuran
State of the art of carbonic anhydrase activators. Future medicinal chemistry (2023)
Michele Aventaggiato, Federica Barreca, Laura Vitiello, Simone Vespa, Sergio Valente, Dante Rotili, Antonello Mai, Lavinia Vittoria Lotti, Luigi Sansone, Matteo Antonio Russo, Mariano Bizzarri, Elisabetta Ferretti, Marco Tafani
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery. Cells 12 (5) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry (2023)
Francesco Fiorentino, Alessio Nocentini, Dante Rotili, Claudiu T Supuran, Antonello Mai
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Vanessa Marchant, Flavia Trionfetti, Lucia Tejedor-Santamaria, Sandra Rayego-Mateos, Dante Rotili, Giulio Bontempi, Alessandro Domenici, Paolo Menè, Antonello Mai, Catalina Martín-Cleary, Alberto Ortiz Arduan, Adrian M Ramos, Raffaele Strippoli, Marta Ruiz-Ortega
BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress. Antioxidants (Basel, Switzerland) 12 (12) (2023)
Francesco Fiorentino, Sara Sementilli, Martina Menna, Federica Turrisi, Stefano Tomassi, Francesca Romana Pellegrini, Angela Iuzzolino, Francesca D'Acunzo, Alessandra Feoli, Hannah Wapenaar, Sophie Taraglio, Caterina Fraschetti, Donatella Del Bufalo, Gianluca Sbardella, Frank J Dekker, Alessandro Paiardini, Daniela Trisciuoglio, Antonello Mai, Dante Rotili
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8. Journal of medicinal chemistry (2023)
Michele Aventaggiato, Federica Barreca, Laura Vitiello, Simone Vespa, Sergio Valente, Dante Rotili, Antonello Mai, Lavinia Vittoria Lotti, Luigi Sansone, Matteo Antonio Russo, Mariano Bizzarri, Elisabetta Ferretti, Marco Tafani
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery. Cells 12 (5) (2023)
Francesco Fiorentino, Alessio Nocentini, Dante Rotili, Claudiu T Supuran, Antonello Mai
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Aide Negri, Marina Marozzi, Daniela Trisciuoglio, Dante Rotili, Antonello Mai, Federica Rizzi
Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Emanuele Fabbrizi, Francesco Fiorentino, Vincenzo Carafa, Lucia Altucci, Antonello Mai, Dante Rotili
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection. Cells 12 (6) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Emanuele Fabbrizi, Francesco Fiorentino, Vincenzo Carafa, Lucia Altucci, Antonello Mai, Dante Rotili
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection. Cells 12 (6) (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Clemens Zwergel, Michele Aventaggiato, Sabrina Garbo, Elisabetta Di Bello, Bruno Fassari, Beatrice Noce, Carola Castiello, Chiara Lambona, Federica Barreca, Dante Rotili, Rossella Fioravanti, Thomas Schmalz, Michael Weyand, Amelie Niedermeier, Marco Tripodi, Gianni Colotti, Clemens Steegborn, Cecilia Battistelli, Marco Tafani, Sergio Valente, Antonello Mai
Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells. Journal of medicinal chemistry (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Aide Negri, Marina Marozzi, Daniela Trisciuoglio, Dante Rotili, Antonello Mai, Federica Rizzi
Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Anna Maggiore, Assunta Maria Casale, Walter Toscanelli, Ugo Cappucci, Dante Rotili, Maddalena Grieco, Jean-Philippe Gagné, Guy G Poirier, Maria d'Erme, Lucia Piacentini
Neuroprotective Effects of PARP Inhibitors in Drosophila Models of Alzheimer's Disease. Cells 11 (8) (2022)
Samanta Taurone, Chiara De Ponte, Dante Rotili, Elena De Santis, Antonello Mai, Francesco Fiorentino, Susanna Scarpa, Marco Artico, Alessandra Micera
Biochemical Functions and Clinical Characterizations of the Sirtuins in Diabetes-Induced Retinal Pathologies. International journal of molecular sciences 23 (7) (2022)
Giulia Siciliano, Veronica Di Paolo, Dante Rotili, Rossella Migale, Francesca Pedini, Marialuisa Casella, Serena Camerini, Daniele Dalzoppo, Rob Henderson, Tonnie Huijs, Koen J Dechering, Antonello Mai, Anna Maria Caccuri, Marco Lalle, Luigi Quintieri, Pietro Alano
The Nitrobenzoxadiazole Derivative NBDHEX Behaves as Plasmodium falciparum Gametocyte Selective Inhibitor with Malaria Parasite Transmission Blocking Activity. Pharmaceuticals (Basel, Switzerland) 15 (2) (2022)
Francesco Fiorentino, Carola Castiello, Antonello Mai, Dante Rotili
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5. Journal of medicinal chemistry 65 (14) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Anastasia Orekhova, Marta De Angelis, Andrea Cacciotti, Massimo Reverberi, Dante Rotili, Alessandra Giorgi, Virginia Protto, Graziana Bonincontro, Francesco Fiorentino, Victor G Zgoda, Antonello Mai, Anna Teresa Palamara, Giovanna Simonetti
Modulation of Virulence-Associated Traits in Aspergillus fumigatus by BET Inhibitor JQ1. Microorganisms 10 (11) (2022)
Francesco Fiorentino, Nicola Mautone, Martina Menna, Francesca D'Acunzo, Antonello Mai, Dante Rotili
Sirtuin modulators: past, present, and future perspectives. Future medicinal chemistry 14 (12) (2022)
Francesco Fiorentino, Marta De Angelis, Martina Menna, Annarita Rovere, Anna Maria Caccuri, Francesca D'Acunzo, Anna Teresa Palamara, Lucia Nencioni, Dante Rotili, Antonello Mai
Anti-influenza A virus activity and structure-activity relationship of a series of nitrobenzoxadiazole derivatives. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2022)
Elisabetta Di Bello, Beatrice Noce, Rossella Fioravanti, Clemens Zwergel, Sergio Valente, Dante Rotili, Giulia Fianco, Daniela Trisciuoglio, Marina M Mourão, Policarpo Sales, Suzanne Lamotte, Eric Prina, Gerald F Späth, Cécile Häberli, Jennifer Keiser, Antonello Mai
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi , Leishmania , and Schistosoma mansoni . ACS infectious diseases 8 (7) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry (2022)
Francesco Fiorentino, Antonello Mai, Dante Rotili
Emerging Therapeutic Potential of SIRT6 Modulators. Journal of medicinal chemistry 64 (14) (2021)
Francesca Molinari, Alessandra Feraco, Simone Mirabilii, Serena Saladini, Luigi Sansone, Enza Vernucci, Giada Tomaselli, Vincenzo Marzolla, Dante Rotili, Matteo Antonio Russo, Maria Rosaria Ricciardi, Agostino Tafuri, Antonello Mai, Massimiliano Caprio, Marco Tafani, Andrea Armani
SIRT5 Inhibition Induces Brown Fat-Like Phenotype in 3T3-L1 Preadipocytes. Cells 10 (5) (2021)
Radosław P Nowak, Anthony Tumber, Eline Hendrix, Mohammad Salik Zeya Ansari, Manuela Sabatino, Lorenzo Antonini, Regina Andrijes, Eidarus Salah, Nicola Mautone, Francesca Romana Pellegrini, Klemensas Simelis, Akane Kawamura, Catrine Johansson, Daniela Passeri, Roberto Pellicciari, Alessia Ciogli, Donatella Del Bufalo, Rino Ragno, Mathew L Coleman, Daniela Trisciuoglio, Antonello Mai, Udo Oppermann, Christopher J Schofield, Dante Rotili
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53. Journal of medicinal chemistry 64 (23) (2021)
Francesco Fiorentino, Dante Rotili, Antonello Mai, Jani Reddy Bolla, Carol V Robinson
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions. Chemical communications (Cambridge, England) 57 (82) (2021)
Rosaria Benedetti, Chiara Papulino, Giulia Sgueglia, Ugo Chianese, Tommaso De Marchi, Francesco Iovino, Dante Rotili, Antonello Mai, Emma Niméus, Carmela Dell'Aversana, Lucia Altucci
Regulatory Interplay between miR-181a-5p and Estrogen Receptor Signaling Cascade in Breast Cancer. Cancers 13 (3) (2021)
Francesco Fiorentino, Vincenzo Carafa, Gregorio Favale, Lucia Altucci, Antonello Mai, Dante Rotili
The Two-Faced Role of SIRT6 in Cancer. Cancers 13 (5) (2021)
Nicola Mautone, Clemens Zwergel, Antonello Mai, Dante Rotili
Sirtuin modulators: where are we now? A review of patents from 2015 to 2019. Expert opinion on therapeutic patents 30 (6) (2020)
Tanira Matutino Bastos, Milena Botelho Pereira Soares, Caio Haddad Franco, Laura Maria Alcântara, Lorenzo Antonini, Manuela Sabatino, Nicola Mautone, Lucio Holanda Freitas-Junior, Carolina Borsoi Moraes, Rino Ragno, Dante Rotili, Sergio Schenkman, Antonello Mai, Nilmar Silvio Moretti
Identification of Inhibitors to Trypanosoma cruzi Sirtuins Based on Compounds Developed to Human Enzymes. International journal of molecular sciences 21 (10) (2020)
Rosaria Benedetti, Carmela Dell'Aversana, Tommaso De Marchi, Dante Rotili, Ning Qing Liu, Boris Novakovic, Serena Boccella, Salvatore Di Maro, Sandro Cosconati, Alfonso Baldi, Emma Niméus, Johan Schultz, Urban Höglund, Sabatino Maione, Chiara Papulino, Ugo Chianese, Francesco Iovino, Antonio Federico, Antonello Mai, Hendrik G Stunnenberg, Angela Nebbioso, Lucia Altucci
Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signaling in Breast Cancer. Cancers 11 (12) (2019)
Vincenzo Carafa, Angelita Poziello, Laura Della Torre, Pia Giovannelli, Marzia Di Donato, Elham Safadeh, Zhijun Yu, Alfonso Baldi, Gabriella Castoria, Daniela Tomaselli, Antonello Mai, Dante Rotili, Angela Nebbioso, Lucia Altucci
Enzymatic and Biological Characterization of Novel Sirtuin Modulators against Cancer. International journal of molecular sciences 20 (22) (2019)
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