Antonello Mai

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 109

Top Venues

Journal of medicinal chemistry

ChemMedChem

Journal of enzyme inhibition and medicinal chemistry

Cells

This page only lists publications with an associated author ORCID identifier.

Publications

Martin Pannek, Zayan Alhalabi, Daniela Tomaselli, Martina Menna, Francesco Fiorentino, Dina Robaa, Michael Weyand, Maximilian Puhlmann, Stefano Tomassi, Federica Barreca, Marco Tafani, Elma Zaganjor, Marcia C Haigis, Wolfgang Sippl, Dante Rotili, Antonello Mai, Clemens Steegborn
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity. Journal of medicinal chemistry 67 (3) (2024)
Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process. Journal of medicinal chemistry 67 (3) (2024)
Clemens Zwergel, Rossella Fioravanti, Giulia Stazi, Federica Sarno, Cecilia Battistelli, Annalisa Romanelli, Angela Nebbioso, Eduarda Mendes, Alexandra Paulo, Raffaele Strippoli, Marco Tripodi, Dany Pechalrieu, Paola Barbara Arimondo, Teresa De Luca, Donatella Del Bufalo, Daniela Trisciuoglio, Lucia Altucci, Sergio Valente, Antonello Mai
Correction: Zwergel et al. Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation. Cancers 2020, 12 , 447. Cancers 16 (6) (2024)
Marie Villares, Nelly Lourenço, Ivan Ktorza, Jérémy Berthelet, Aristeidis Panagiotou, Aurélie Richard, Angélique Amo, Yulianna Koziy, Souhila Medjkane, Sergio Valente, Rossella Fioravanti, Catherine Pioche-Durieu, Laurent Lignière, Guillaume Chevreux, Antonello Mai, Jonathan B Weitzman
Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy. Nature communications 15 (1) (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Antonello Mai, Dante Rotili
Activation and inhibition of sirtuins: From bench to bedside. Medicinal research reviews (2024)
Clemens Zwergel, Rossella Fioravanti, Giulia Stazi, Federica Sarno, Cecilia Battistelli, Annalisa Romanelli, Angela Nebbioso, Eduarda Mendes, Alexandra Paulo, Raffaele Strippoli, Marco Tripodi, Dany Pechalrieu, Paola Barbara Arimondo, Teresa De Luca, Donatella Del Bufalo, Daniela Trisciuoglio, Lucia Altucci, Sergio Valente, Antonello Mai
Correction: Zwergel et al. Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation. Cancers 2020, 12 , 447. Cancers 16 (6) (2024)
Marie Villares, Nelly Lourenço, Ivan Ktorza, Jérémy Berthelet, Aristeidis Panagiotou, Aurélie Richard, Angélique Amo, Yulianna Koziy, Souhila Medjkane, Sergio Valente, Rossella Fioravanti, Catherine Pioche-Durieu, Laurent Lignière, Guillaume Chevreux, Antonello Mai, Jonathan B Weitzman
Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy. Nature communications 15 (1) (2024)
Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process. Journal of medicinal chemistry 67 (3) (2024)
Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process. Journal of medicinal chemistry (2024)
Marie Villares, Nelly Lourenço, Ivan Ktorza, Jérémy Berthelet, Aristeidis Panagiotou, Aurélie Richard, Angélique Amo, Yulianna Koziy, Souhila Medjkane, Sergio Valente, Rossella Fioravanti, Catherine Pioche-Durieu, Laurent Lignière, Guillaume Chevreux, Antonello Mai, Jonathan B Weitzman
Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy. Nature communications 15 (1) (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Alessia Raucci, Beatrice Noce, Rossella Fioravanti, Sergio Valente, Chantal Paolini, Ruggero De Maria, Christian Steinkühler, Paola Gallinari, Dante Rotili, Antonello Mai
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells. ChemMedChem 19 (13) (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Alessia Raucci, Beatrice Noce, Rossella Fioravanti, Sergio Valente, Chantal Paolini, Ruggero De Maria, Christian Steinkühler, Paola Gallinari, Dante Rotili, Antonello Mai
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells. ChemMedChem 19 (13) (2024)
Michele Aventaggiato, Tania Arcangeli, Enza Vernucci, Federica Barreca, Luigi Sansone, Laura Pellegrini, Elena Pontemezzo, Sergio Valente, Rossella Fioravanti, Matteo Antonio Russo, Antonello Mai, Marco Tafani
Pharmacological Activation of SIRT3 Modulates the Response of Cancer Cells to Acidic pH. Pharmaceuticals (Basel, Switzerland) 17 (6) (2024)
Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process. Journal of medicinal chemistry 67 (3) (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Alessia Raucci, Beatrice Noce, Rossella Fioravanti, Sergio Valente, Chantal Paolini, Ruggero De Maria, Christian Steinkühler, Paola Gallinari, Dante Rotili, Antonello Mai
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells. ChemMedChem (2024)
Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process. Journal of medicinal chemistry 67 (3) (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Alessia Raucci, Beatrice Noce, Rossella Fioravanti, Sergio Valente, Chantal Paolini, Ruggero De Maria, Christian Steinkühler, Paola Gallinari, Dante Rotili, Antonello Mai
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells. ChemMedChem 19 (13) (2024)
Jujun Zhou, Qin Chen, Ren Ren, Jie Yang, Bigang Liu, John R Horton, Caleb Chang, Chuxuan Li, Leora Maksoud, Yifei Yang, Dante Rotili, Xing Zhang, Robert M Blumenthal, Jiameng Dan, Yang Gao, Sergio Valente, Antonello Mai, Xiaodong Cheng
Quinoline-based compounds can inhibit diverse enzymes that act on DNA. bioRxiv : the preprint server for biology (2024)
Alessia Raucci, Carola Castiello, Antonello Mai, Clemens Zwergel, Sergio Valente
Heterocycles-Containing HDAC Inhibitors Active in Cancer: An Overview of the Last Fifteen Years. ChemMedChem (2024)
Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process. Journal of medicinal chemistry 67 (3) (2024)
Martin Pannek, Zayan Alhalabi, Daniela Tomaselli, Martina Menna, Francesco Fiorentino, Dina Robaa, Michael Weyand, Maximilian Puhlmann, Stefano Tomassi, Federica Barreca, Marco Tafani, Elma Zaganjor, Marcia C Haigis, Wolfgang Sippl, Dante Rotili, Antonello Mai, Clemens Steegborn
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity. Journal of medicinal chemistry (2024)
Martin Pannek, Zayan Alhalabi, Daniela Tomaselli, Martina Menna, Francesco Fiorentino, Dina Robaa, Michael Weyand, Maximilian Puhlmann, Stefano Tomassi, Federica Barreca, Marco Tafani, Elma Zaganjor, Marcia C Haigis, Wolfgang Sippl, Dante Rotili, Antonello Mai, Clemens Steegborn
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity. Journal of medicinal chemistry 67 (3) (2024)
Francesco Fiorentino, Alessio Nocentini, Dante Rotili, Claudiu T Supuran, Antonello Mai
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Francesco Fiorentino, Sara Sementilli, Martina Menna, Federica Turrisi, Stefano Tomassi, Francesca Romana Pellegrini, Angela Iuzzolino, Francesca D'Acunzo, Alessandra Feoli, Hannah Wapenaar, Sophie Taraglio, Caterina Fraschetti, Donatella Del Bufalo, Gianluca Sbardella, Frank J Dekker, Alessandro Paiardini, Daniela Trisciuoglio, Antonello Mai, Dante Rotili
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8. Journal of medicinal chemistry (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Emanuele Fabbrizi, Francesco Fiorentino, Vincenzo Carafa, Lucia Altucci, Antonello Mai, Dante Rotili
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection. Cells 12 (6) (2023)
Michele Aventaggiato, Federica Barreca, Laura Vitiello, Simone Vespa, Sergio Valente, Dante Rotili, Antonello Mai, Lavinia Vittoria Lotti, Luigi Sansone, Matteo Antonio Russo, Mariano Bizzarri, Elisabetta Ferretti, Marco Tafani
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery. Cells 12 (5) (2023)
Aide Negri, Marina Marozzi, Daniela Trisciuoglio, Dante Rotili, Antonello Mai, Federica Rizzi
Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Vanessa Marchant, Flavia Trionfetti, Lucia Tejedor-Santamaria, Sandra Rayego-Mateos, Dante Rotili, Giulio Bontempi, Alessandro Domenici, Paolo Menè, Antonello Mai, Catalina Martín-Cleary, Alberto Ortiz Arduan, Adrian M Ramos, Raffaele Strippoli, Marta Ruiz-Ortega
BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress. Antioxidants (Basel, Switzerland) 12 (12) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Michele Aventaggiato, Federica Barreca, Laura Vitiello, Simone Vespa, Sergio Valente, Dante Rotili, Antonello Mai, Lavinia Vittoria Lotti, Luigi Sansone, Matteo Antonio Russo, Mariano Bizzarri, Elisabetta Ferretti, Marco Tafani
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery. Cells 12 (5) (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Joana Reis, Christoph Gorgulla, Marta Massari, Sara Marchese, Sergio Valente, Beatrice Noce, Lorenzo Basile, Ricarda Törner, Huel Cox, Thibault Viennet, Moon Hee Yang, Melissa A Ronan, Matthew G Rees, Jennifer A Roth, Lucia Capasso, Angela Nebbioso, Lucia Altucci, Antonello Mai, Haribabu Arthanari, Andrea Mattevi
Targeting ROS production through inhibition of NADPH oxidases. Nature chemical biology (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Francesco Fiorentino, Fabrizio Carta, Dante Rotili, Antonello Mai, Claudiu T Supuran
State of the art of carbonic anhydrase activators. Future medicinal chemistry (2023)
Michele Aventaggiato, Federica Barreca, Laura Vitiello, Simone Vespa, Sergio Valente, Dante Rotili, Antonello Mai, Lavinia Vittoria Lotti, Luigi Sansone, Matteo Antonio Russo, Mariano Bizzarri, Elisabetta Ferretti, Marco Tafani
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery. Cells 12 (5) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry (2023)
Francesco Fiorentino, Alessio Nocentini, Dante Rotili, Claudiu T Supuran, Antonello Mai
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Vanessa Marchant, Flavia Trionfetti, Lucia Tejedor-Santamaria, Sandra Rayego-Mateos, Dante Rotili, Giulio Bontempi, Alessandro Domenici, Paolo Menè, Antonello Mai, Catalina Martín-Cleary, Alberto Ortiz Arduan, Adrian M Ramos, Raffaele Strippoli, Marta Ruiz-Ortega
BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress. Antioxidants (Basel, Switzerland) 12 (12) (2023)
Francesco Fiorentino, Sara Sementilli, Martina Menna, Federica Turrisi, Stefano Tomassi, Francesca Romana Pellegrini, Angela Iuzzolino, Francesca D'Acunzo, Alessandra Feoli, Hannah Wapenaar, Sophie Taraglio, Caterina Fraschetti, Donatella Del Bufalo, Gianluca Sbardella, Frank J Dekker, Alessandro Paiardini, Daniela Trisciuoglio, Antonello Mai, Dante Rotili
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8. Journal of medicinal chemistry (2023)
Michele Aventaggiato, Federica Barreca, Laura Vitiello, Simone Vespa, Sergio Valente, Dante Rotili, Antonello Mai, Lavinia Vittoria Lotti, Luigi Sansone, Matteo Antonio Russo, Mariano Bizzarri, Elisabetta Ferretti, Marco Tafani
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery. Cells 12 (5) (2023)
Federica Barreca, Michele Aventaggiato, Laura Vitiello, Luigi Sansone, Matteo Antonio Russo, Antonello Mai, Sergio Valente, Marco Tafani
SIRT5 Activation and Inorganic Phosphate Binding Reduce Cancer Cell Vitality by Modulating Autophagy/Mitophagy and ROS. Antioxidants (Basel, Switzerland) 12 (8) (2023)
Francesco Fiorentino, Alessio Nocentini, Dante Rotili, Claudiu T Supuran, Antonello Mai
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Aide Negri, Marina Marozzi, Daniela Trisciuoglio, Dante Rotili, Antonello Mai, Federica Rizzi
Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Emanuele Fabbrizi, Francesco Fiorentino, Vincenzo Carafa, Lucia Altucci, Antonello Mai, Dante Rotili
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection. Cells 12 (6) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Emanuele Fabbrizi, Francesco Fiorentino, Vincenzo Carafa, Lucia Altucci, Antonello Mai, Dante Rotili
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection. Cells 12 (6) (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Clemens Zwergel, Michele Aventaggiato, Sabrina Garbo, Elisabetta Di Bello, Bruno Fassari, Beatrice Noce, Carola Castiello, Chiara Lambona, Federica Barreca, Dante Rotili, Rossella Fioravanti, Thomas Schmalz, Michael Weyand, Amelie Niedermeier, Marco Tripodi, Gianni Colotti, Clemens Steegborn, Cecilia Battistelli, Marco Tafani, Sergio Valente, Antonello Mai
Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells. Journal of medicinal chemistry (2023)
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu, Taraneh Hajian, Masoud Vedadi, Dante Rotili, Antonello Mai, Robert M Blumenthal, Xing Zhang, Rong Huang, Xiaodong Cheng
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase. ACS chemical biology 18 (4) (2023)
Aide Negri, Marina Marozzi, Daniela Trisciuoglio, Dante Rotili, Antonello Mai, Federica Rizzi
Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Giulia Stazi, Ludovica Taglieri, Alice Nicolai, Annalisa Romanelli, Rossella Fioravanti, Stefania Morrone, Manuela Sabatino, Rino Ragno, Samanta Taurone, Marcella Nebbioso, Raffaella Carletti, Marco Artico, Sergio Valente, Susanna Scarpa, Antonello Mai
Retraction Note: Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelialmesenchymal transition, migration, and on the pro-inflammatory phenotype. Clinical epigenetics 15 (1) (2023)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Samanta Taurone, Chiara De Ponte, Dante Rotili, Elena De Santis, Antonello Mai, Francesco Fiorentino, Susanna Scarpa, Marco Artico, Alessandra Micera
Biochemical Functions and Clinical Characterizations of the Sirtuins in Diabetes-Induced Retinal Pathologies. International journal of molecular sciences 23 (7) (2022)
Giulia Siciliano, Veronica Di Paolo, Dante Rotili, Rossella Migale, Francesca Pedini, Marialuisa Casella, Serena Camerini, Daniele Dalzoppo, Rob Henderson, Tonnie Huijs, Koen J Dechering, Antonello Mai, Anna Maria Caccuri, Marco Lalle, Luigi Quintieri, Pietro Alano
The Nitrobenzoxadiazole Derivative NBDHEX Behaves as Plasmodium falciparum Gametocyte Selective Inhibitor with Malaria Parasite Transmission Blocking Activity. Pharmaceuticals (Basel, Switzerland) 15 (2) (2022)
Jacopo Morroni, Leonardo Schirone, Valentina Valenti, Clemens Zwergel, Carles Sánchez Riera, Sergio Valente, Daniele Vecchio, Sonia Schiavon, Rino Ragno, Antonello Mai, Sebastiano Sciarretta, Biliana Lozanoska-Ochser, Marina Bouché
Inhibition of PKCθ Improves Dystrophic Heart Phenotype and Function in a Novel Model of DMD Cardiomyopathy. International journal of molecular sciences 23 (4) (2022)
Rossella Fioravanti, Veronica Rodriguez, Jonatan Caroli, Ugo Chianese, Rosaria Benedetti, Elisabetta Di Bello, Beatrice Noce, Clemens Zwergel, Davide Corinti, Dolores Viña, Lucia Altucci, Andrea Mattevi, Sergio Valente, Antonello Mai
Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Francesco Fiorentino, Carola Castiello, Antonello Mai, Dante Rotili
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5. Journal of medicinal chemistry 65 (14) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Benjamin Suenkel, Sergio Valente, Clemens Zwergel, Sandra Weiss, Elisabetta Di Bello, Rossella Fioravanti, Michele Aventaggiato, João A Amorim, Neha Garg, Surinder Kumar, David B Lombard, Tuo Hu, Pankaj K Singh, Marco Tafani, Carlos M Palmeira, David Sinclair, Antonello Mai, Clemens Steegborn
Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5. Journal of medicinal chemistry 65 (20) (2022)
Anastasia Orekhova, Marta De Angelis, Andrea Cacciotti, Massimo Reverberi, Dante Rotili, Alessandra Giorgi, Virginia Protto, Graziana Bonincontro, Francesco Fiorentino, Victor G Zgoda, Antonello Mai, Anna Teresa Palamara, Giovanna Simonetti
Modulation of Virulence-Associated Traits in Aspergillus fumigatus by BET Inhibitor JQ1. Microorganisms 10 (11) (2022)
Francesco Fiorentino, Nicola Mautone, Martina Menna, Francesca D'Acunzo, Antonello Mai, Dante Rotili
Sirtuin modulators: past, present, and future perspectives. Future medicinal chemistry 14 (12) (2022)
Francesco Fiorentino, Marta De Angelis, Martina Menna, Annarita Rovere, Anna Maria Caccuri, Francesca D'Acunzo, Anna Teresa Palamara, Lucia Nencioni, Dante Rotili, Antonello Mai
Anti-influenza A virus activity and structure-activity relationship of a series of nitrobenzoxadiazole derivatives. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2022)
Silvia Consalvi, Luca Tucciarone, Elisa Macrì, Marco De Bardi, Mario Picozza, Illari Salvatori, Alessandra Renzini, Sergio Valente, Antonello Mai, Viviana Moresi, Pier Lorenzo Puri
Determinants of epigenetic resistance to HDAC inhibitors in dystrophic fibro-adipogenic progenitors. EMBO reports 23 (6) (2022)
Elisabetta Di Bello, Beatrice Noce, Rossella Fioravanti, Clemens Zwergel, Sergio Valente, Dante Rotili, Giulia Fianco, Daniela Trisciuoglio, Marina M Mourão, Policarpo Sales, Suzanne Lamotte, Eric Prina, Gerald F Späth, Cécile Häberli, Jennifer Keiser, Antonello Mai
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi , Leishmania , and Schistosoma mansoni . ACS infectious diseases 8 (7) (2022)
Beatrice Noce, Elisabetta Di Bello, Clemens Zwergel, Rossella Fioravanti, Sergio Valente, Dante Rotili, Andrea Masotti, Mohammad Salik Zeya Ansari, Daniela Trisciuoglio, Alokta Chakrabarti, Christophe Romier, Dina Robaa, Wolfgang Sippl, Manfred Jung, Cécile Häberli, Jennifer Keiser, Antonello Mai
Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages. ChemMedChem (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry (2022)
Francesco Fiorentino, Antonello Mai, Dante Rotili
Emerging Therapeutic Potential of SIRT6 Modulators. Journal of medicinal chemistry 64 (14) (2021)
Francesca Molinari, Alessandra Feraco, Simone Mirabilii, Serena Saladini, Luigi Sansone, Enza Vernucci, Giada Tomaselli, Vincenzo Marzolla, Dante Rotili, Matteo Antonio Russo, Maria Rosaria Ricciardi, Agostino Tafuri, Antonello Mai, Massimiliano Caprio, Marco Tafani, Andrea Armani
SIRT5 Inhibition Induces Brown Fat-Like Phenotype in 3T3-L1 Preadipocytes. Cells 10 (5) (2021)
Radosław P Nowak, Anthony Tumber, Eline Hendrix, Mohammad Salik Zeya Ansari, Manuela Sabatino, Lorenzo Antonini, Regina Andrijes, Eidarus Salah, Nicola Mautone, Francesca Romana Pellegrini, Klemensas Simelis, Akane Kawamura, Catrine Johansson, Daniela Passeri, Roberto Pellicciari, Alessia Ciogli, Donatella Del Bufalo, Rino Ragno, Mathew L Coleman, Daniela Trisciuoglio, Antonello Mai, Udo Oppermann, Christopher J Schofield, Dante Rotili
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53. Journal of medicinal chemistry 64 (23) (2021)
Francesco Fiorentino, Dante Rotili, Antonello Mai, Jani Reddy Bolla, Carol V Robinson
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions. Chemical communications (Cambridge, England) 57 (82) (2021)
Rosaria Benedetti, Chiara Papulino, Giulia Sgueglia, Ugo Chianese, Tommaso De Marchi, Francesco Iovino, Dante Rotili, Antonello Mai, Emma Niméus, Carmela Dell'Aversana, Lucia Altucci
Regulatory Interplay between miR-181a-5p and Estrogen Receptor Signaling Cascade in Breast Cancer. Cancers 13 (3) (2021)
Francesco Fiorentino, Vincenzo Carafa, Gregorio Favale, Lucia Altucci, Antonello Mai, Dante Rotili
The Two-Faced Role of SIRT6 in Cancer. Cancers 13 (5) (2021)
Stefano Tomassi, Annalisa Romanelli, Clemens Zwergel, Sergio Valente, Antonello Mai
Polycomb Repressive Complex 2 Modulation through the Development of EZH2-EED Interaction Inhibitors and EED Binders. Journal of medicinal chemistry 64 (16) (2021)
Nicola Mautone, Clemens Zwergel, Antonello Mai, Dante Rotili
Sirtuin modulators: where are we now? A review of patents from 2015 to 2019. Expert opinion on therapeutic patents 30 (6) (2020)
Silvia Caroselli, Clemens Zwergel, Adele Pirolli, Manuela Sabatino, Zhanjie Xu, Gilbert Kirsch, Antonello Mai, Gianni Colotti, Fabio Altieri, Rita Canipari, Sergio Valente, Rino Ragno
Discovery of the First Human Arylsulfatase A Reversible Inhibitor Impairing Mouse Oocyte Fertilization. ACS chemical biology 15 (6) (2020)
Rossella Fioravanti, Annalisa Romanelli, Nicola Mautone, Elisabetta Di Bello, Annarita Rovere, Davide Corinti, Clemens Zwergel, Sergio Valente, Dante Rotili, Oronza A Botrugno, Paola Dessanti, Stefania Vultaggio, Paola Vianello, Anna Cappa, Claudia Binda, Andrea Mattevi, Saverio Minucci, Ciro Mercurio, Mario Varasi, Antonello Mai
Tranylcypromine-Based LSD1 Inhibitors: Structure-Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation. ChemMedChem 15 (7) (2020)
Evelina Miele, Agnese Pò, Angela Mastronuzzi, Andrea Carai, Zein Mersini Besharat, Natalia Pediconi, Luana Abballe, Giuseppina Catanzaro, Claudia Sabato, Enrico De Smaele, Gianluca Canettieri, Lucia Di Marcotullio, Alessandra Vacca, Antonello Mai, Massimo Levrero, Stefan M Pfister, Marcel Kool, Felice Giangaspero, Franco Locatelli, Elisabetta Ferretti
Downregulation of miR-326 and its host gene β-arrestin1 induces pro-survival activity of E2F1 and promotes medulloblastoma growth. Molecular oncology 15 (2) (2020)
Tanira Matutino Bastos, Milena Botelho Pereira Soares, Caio Haddad Franco, Laura Maria Alcântara, Lorenzo Antonini, Manuela Sabatino, Nicola Mautone, Lucio Holanda Freitas-Junior, Carolina Borsoi Moraes, Rino Ragno, Dante Rotili, Sergio Schenkman, Antonello Mai, Nilmar Silvio Moretti
Identification of Inhibitors to Trypanosoma cruzi Sirtuins Based on Compounds Developed to Human Enzymes. International journal of molecular sciences 21 (10) (2020)
Rossella Fioravanti, Stefano Tomassi, Elisabetta Di Bello, Annalisa Romanelli, Andrea Maria Plateroti, Rosaria Benedetti, Mariarosaria Conte, Ettore Novellino, Lucia Altucci, Sergio Valente, Antonello Mai
Properly Substituted Cyclic Bis-(2-bromobenzylidene) Compounds Behaved as Dual p300/CARM1 Inhibitors and Induced Apoptosis in Cancer Cells. Molecules (Basel, Switzerland) 25 (14) (2020)
Roberto Ravasio, Elena Ceccacci, Luciano Nicosia, Amir Hosseini, Pier Luigi Rossi, Iros Barozzi, Lorenzo Fornasari, Roberto Dal Zuffo, Sergio Valente, Rossella Fioravanti, Ciro Mercurio, Mario Varasi, Andrea Mattevi, Antonello Mai, Giulio Pavesi, Tiziana Bonaldi, Saverio Minucci
Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation. Science advances 6 (15) (2020)
Angela Nebbioso, Fabio Manzo, Marco Miceli, Mariarosaria Conte, Lucrezia Manente, Alfonso Baldi, Antonio De Luca, Dante Rotili, Sergio Valente, Antonello Mai, Alessandro Usiello, Hinrich Gronemeyer, Lucia Altucci
Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes. EMBO reports 21 (12) (2020)
Vitor Coutinho Carneiro, Isabel Caetano de Abreu da Silva, Murilo Sena Amaral, Adriana S A Pereira, Gilbert Oliveira Silveira, David da Silva Pires, Sergio Verjovski-Almeida, Frank J Dekker, Dante Rotili, Antonello Mai, Eduardo José Lopes-Torres, Dina Robaa, Wolfgang Sippl, Raymond J Pierce, María Teresa Borrello, Arasu Ganesan, Julien Lancelot, Silvana Carvalho Thiengo, Monica Ammon Fernandez, Amanda Roberta Revoredo Vicentino, Marina Moraes Mourão, Fernanda Sales Coelho, Marcelo Rosado Fantappié
Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni. PLoS neglected tropical diseases 14 (7) (2020)
Rosaria Benedetti, Carmela Dell'Aversana, Tommaso De Marchi, Dante Rotili, Ning Qing Liu, Boris Novakovic, Serena Boccella, Salvatore Di Maro, Sandro Cosconati, Alfonso Baldi, Emma Niméus, Johan Schultz, Urban Höglund, Sabatino Maione, Chiara Papulino, Ugo Chianese, Francesco Iovino, Antonio Federico, Antonello Mai, Hendrik G Stunnenberg, Angela Nebbioso, Lucia Altucci
Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signaling in Breast Cancer. Cancers 11 (12) (2019)
Annarita Favia, Luisa Salvatori, Simona Nanni, Lisa K Iwamoto-Stohl, Sergio Valente, Antonello Mai, Fiorella Scagnoli, Rosaria Anna Fontanella, Pierangela Totta, Sergio Nasi, Barbara Illi
The Protein Arginine Methyltransferases 1 and 5 affect Myc properties in glioblastoma stem cells. Scientific reports 9 (1) (2019)
Vincenzo Carafa, Angelita Poziello, Laura Della Torre, Pia Giovannelli, Marzia Di Donato, Elham Safadeh, Zhijun Yu, Alfonso Baldi, Gabriella Castoria, Daniela Tomaselli, Antonello Mai, Dante Rotili, Angela Nebbioso, Lucia Altucci
Enzymatic and Biological Characterization of Novel Sirtuin Modulators against Cancer. International journal of molecular sciences 20 (22) (2019)
Paolo Mellini, Biagina Marrocco, Diana Borovika, Lucia Polletta, Ilaria Carnevale, Serena Saladini, Giulia Stazi, Clemens Zwergel, Peteris Trapencieris, Elisabetta Ferretti, Marco Tafani, Sergio Valente, Antonello Mai
Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 373 (1748) (2019)
Giulia Stazi, Ludovica Taglieri, Alice Nicolai, Annalisa Romanelli, Rossella Fioravanti, Stefania Morrone, Manuela Sabatino, Rino Ragno, Samanta Taurone, Marcella Nebbioso, Raffaella Carletti, Marco Artico, Sergio Valente, Susanna Scarpa, Antonello Mai
Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype. Clinical epigenetics 11 (1) (2019)
Daniela Tomaselli, Alessia Lucidi, Dante Rotili, Antonello Mai
Epigenetic polypharmacology: A new frontier for epi-drug discovery. Medicinal research reviews 40 (1) (2019)
Daria Monaldi, Dante Rotili, Julien Lancelot, Martin Marek, Nathalie Wössner, Alessia Lucidi, Daniela Tomaselli, Elizabeth Ramos-Morales, Christophe Romier, Raymond J Pierce, Antonello Mai, Manfred Jung
Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from Schistosoma mansoni (SmSirt2). Journal of medicinal chemistry 62 (19) (2019)
Roberta Mazzone, Clemens Zwergel, Marco Artico, Samanta Taurone, Massimo Ralli, Antonio Greco, Antonello Mai
The emerging role of epigenetics in human autoimmune disorders. Clinical epigenetics 11 (1) (2019)
Lucia Rossi, Cecilia Battistelli, Valeria de Turris, Valeria Noce, Clemens Zwergel, Sergio Valente, Alessandra Moioli, Andrea Manzione, Marco Palladino, Veronica Bordoni, Alessandro Domenici, Paolo Menè, Antonello Mai, Marco Tripodi, Raffaele Strippoli
HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal. Scientific reports 8 (1) (2018)

Antonello Mai.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Antonello Mai