Evaluation of serum miRNAs expression in frail and robust subjects undergoing multicomponent exercise protocol (VIVIFRAIL).

Simone AgostiniRoberta MancusoLorenzo Agostino CitterioGabriela Alexandra MihaliBeatrice ArosioMario Clerici

Published in: Journal of translational medicine (2023)

These results suggest that serum miR-451a should be investigated as a potential biomarker for frailty and show that the VIVIFRAIL multicomponent program modulates circulatory miRNAs expression, at least in older adults.

Keyphrases

poor prognosis
long non coding rna
physical activity
randomized controlled trial
binding protein
high intensity
quality improvement
extracorporeal membrane oxygenation
high resolution