Effects of probiotic Bifidobacterium bifidum G9-1 on the gastrointestinal symptoms of patients with type 2 diabetes mellitus treated with metformin: An open-label, single-arm, exploratory research trial.
Shinnosuke HataHanako NakajimaYoshitaka HashimotoTomoki MiyoshiYukako HosomiTakuro OkamuraSaori MajimaNaoko NakanishiTakafumi SenmaruTakafumi OsakaHiroshi OkadaEmi UshigomeYoshitaka HashimotoMai AsanoMasahiro YamazakiMichiaki FukuiPublished in: Journal of diabetes investigation (2021)
Type 2 diabetes mellitus patients treated with metformin showed significant improvement in all gastrointestinal symptom rating scores after using probiotic BBG9-1 without changing the glucose control. This study showed the potential usefulness of probiotic BBG9-1 for improving gastrointestinal symptoms, including constipation and diarrhea, in type 2 diabetes mellitus patients treated with metformin.
Keyphrases
- end stage renal disease
- newly diagnosed
- bacillus subtilis
- chronic kidney disease
- ejection fraction
- irritable bowel syndrome
- clinical trial
- peritoneal dialysis
- study protocol
- prognostic factors
- patient reported
- randomized controlled trial
- lactic acid
- phase iii
- metabolic syndrome
- blood pressure
- blood glucose
- adipose tissue
- physical activity
- patient reported outcomes
- human health
- climate change
- clostridium difficile