Effects of Intravesical Lactobacillus Rhamnosus GG on Urinary Symptom Burden in People with Neurogenic Lower Urinary Tract Dysfunction.

Rochelle E TractenbergSuzanne L GroahJamie K FrostAmanda K RoundsElizabeth DavisInger H LjungbergManon M Schladen

Published in: PM & R : the journal of injury, function, and rehabilitation (2020)

Self-instilled LGG seemed to improve "clinically actionable" (A) and "urine quality" (B2) symptom burden. No changes were observed for those who did not instill. This first-in-human clinical trial supports ongoing research of intravesical LGG, and the SMP-Pro for urinary symptoms.

Keyphrases

urinary tract
clinical trial
endothelial cells
spinal cord injury
patient reported
risk factors
induced pluripotent stem cells
oxidative stress
pluripotent stem cells
study protocol
anti inflammatory
open label
lactic acid