Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data.

Lars RejnmarkLise Sofie BislevKevin D CashmanGudny EiríksdottirMartin GakschMartin GrüblerGuri GrimnesVilmundur GudnasonPaul LipsStefan PilzNatasja M van SchoorMairead KielyRolf Jorde

Published in: PloS one (2017)

Published RCTs have mostly been performed in populations without low 25OHD levels. The fact that most MAs on results from RCTs did not show a beneficial effect does not disprove the hypothesis suggested by observational findings on adverse health outcomes of low 25OHD levels.

Keyphrases

meta analyses
systematic review
randomized controlled trial
clinical trial
emergency department
cross sectional
phase ii
data analysis
artificial intelligence