Substance P and Calcitonin gene-related peptide expression in human periodontal ligament after root canal preparation with Reciproc Blue, WaveOne Gold, XP EndoShaper and hand files.
Javier Caviedes BrucheliN Rios-OsorioM Rey-RojasF Laguna-RiveroM M Azuero-HolguinL E DiazH CurtidorJ J Castaneda-RamirezH R MunozPublished in: International endodontic journal (2018)
All the root canal preparation techniques tested increased SP and CGRP expression in human periodontal ligament, with hand files and XP EndoShaper instruments being associated with greater neuropeptide release compared to Reciproc Blue and WaveOne Gold files.