Palmitic acid promotes miRNA release from adipocyte exosomes by activating NF-κB/ER stress.
Menghuan LiYanting HouYao ChenChaoyue SunMaodi LiangXiaolong ChuXin WenFangyuan YuanChaoling PengCuizhe WangJianxin XieJun ZhangPublished in: Nutrition & diabetes (2024)
Obesity-induced increases in PA content increase the expression and release of miRNAs in adipocyte exosomes by activating the NF-κB/ER stress pathway.
Keyphrases
- signaling pathway
- insulin resistance
- adipose tissue
- mesenchymal stem cells
- pi k akt
- stem cells
- lps induced
- fatty acid
- metabolic syndrome
- poor prognosis
- high fat diet induced
- type diabetes
- diabetic rats
- skeletal muscle
- oxidative stress
- high glucose
- nuclear factor
- drug induced
- weight gain
- inflammatory response
- long non coding rna
- cell proliferation
- bone marrow
- endothelial cells
- immune response
- toll like receptor