Bioengineered angiotensin-converting-enzyme-2: a potential therapeutic option against SARS-CoV-2 infection.

Published in: Journal of human hypertension (2021)

The recombinant soluble human angiotensin-converting enzyme 2 (rshACE2) is a promising therapy against SARS-CoV-2 infection, but it has some drawbacks that reduce the success of its clinical applications. The bioengineered ACE2 (Tag-sACE2 and probiotic-ACE2) as a way may overcome its therapeutic limitations against ongoing current pandemic.

Keyphrases

angiotensin converting enzyme
angiotensin ii
respiratory syndrome coronavirus
sars cov
coronavirus disease
endothelial cells
induced pluripotent stem cells
pluripotent stem cells
cell free
mesenchymal stem cells
lactic acid