Effectiveness of first-line treatment for relapsing-remitting multiple sclerosis in Brazil: A 16-year non-concurrent cohort study.

Kathiaja Miranda SouzaIsabela Maia DinizLívia Lovato Pires de LemosNélio Gomes Ribeiro JuniorIsabella de Figueiredo ZuppoJuliana Alvares TeodoroFrancisco de Assis AcurcioÁlvaro Nagib AtallahAugusto Afonso Guerra Júnior

Published in: PloS one (2020)

This retrospective cohort suggests that glatiramer is associated with greater effectiveness compared to the three presentations of interferon beta. When evaluating beta interferons, the results suggest that the intramuscular presentation is not effective in the treatment of multiple sclerosis.

Keyphrases

multiple sclerosis
randomized controlled trial
systematic review
white matter
dendritic cells
cross sectional
case report
locally advanced
immune response
combination therapy
radiation therapy