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Potential therapeutic targets for lung repair during human ex vivo lung perfusion.

Aaron WongRicardo ZamelJonathan YeungGary D BaiderClaudia C Dos SantosXiaohui BaiYubo WangShaf KeshavjeeMingyao Liu
Published in: The European respiratory journal (2020)
EVLP and transplantation share common molecular features of injury including innate inflammation and cell death. Blocking these pathways during EVLP may allow for lung repair prior to transplantation.
Keyphrases
  • cell death
  • immune response
  • endothelial cells
  • oxidative stress
  • stem cells
  • computed tomography
  • cell proliferation
  • cell cycle arrest
  • pluripotent stem cells
  • pi k akt