Human papillomavirus DNA and p16 expression in head and neck squamous cell carcinoma in young French patients.

Chloé MolimardVirginie L'HuillierAlexis OversChristine SoretMarie-Paule AlgrosChristiane MouginDavid GuenatOlivier MauvaisJean-Luc Prétet

Published in: The Journal of international medical research (2021)

HPV-positivity and p16 expression were similar in both age groups. The results suggest that p16 immunohistochemistry may provide a prognosis biomarker for all HNSCCs, not only oropharyngeal cancers, and this should be addressed in large clinical trials.

Keyphrases

poor prognosis
clinical trial
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
binding protein
peritoneal dialysis
randomized controlled trial
patient reported outcomes
long non coding rna
cell free
young adults
double blind