CD47 expression is critical for CAR T-cell survival in vivo.
Alex N BeckettPeter J ChockleyShondra M Pruett-MillerPhuong NguyenPeter VogelHeather SheppardGiedre KrenciuteStephen GottschalkChristopher DeRenzoPublished in: Journal for immunotherapy of cancer (2023)
These findings highlight that CD47 expression is critical for CAR T-cell survival in vivo and is a 'sine qua non' for successful adoptive T-cell therapy.