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CD47 expression is critical for CAR T-cell survival in vivo.

Alex N BeckettPeter J ChockleyShondra M Pruett-MillerPhuong NguyenPeter VogelHeather SheppardGiedre KrenciuteStephen GottschalkChristopher DeRenzo
Published in: Journal for immunotherapy of cancer (2023)
These findings highlight that CD47 expression is critical for CAR T-cell survival in vivo and is a 'sine qua non' for successful adoptive T-cell therapy.
Keyphrases
  • cell therapy
  • poor prognosis
  • stem cells
  • mesenchymal stem cells
  • binding protein
  • long non coding rna
  • nk cells
  • bone marrow