Stephen Gottschalk (Stephen Gottshalk)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 68

Top Topics

Acute Myeloid Leukemia

Top Venues

Nature communications

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Akshay Sharma, Subodh R Selukar, Yu Bi, Anthony Merlocco, Cara E Morin, Chris Goode, Parul Rai, Jeffrey Allen Towbin, Jane Silva Hankins, Stephen Gottschalk, Brandon M Triplett, Jason Nathaniel Johnson
Impact of Hematopoietic Cell Transplantation on Myocardial Fibrosis in Young Patients with Sickle Cell Disease. Blood (2024)
Timothy I Shaw, Jessica Wagner, Liqing Tian, Elizabeth Wickman, Suresh Poudel, Jian Wang, Robin Paul, Selene C Koo, Meifen Lu, Heather Sheppard, Yiping Fan, Francis O'Neil, Ching C Lau, Xin Zhou, Jinghui Zhang, Stephen Gottschalk
Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression. Research square (2024)
Akshay Sharma, Subodh R Selukar, Yu Bi, Anthony Merlocco, Cara E Morin, Chris Goode, Parul Rai, Jeffrey A Towbin, Jane Silva Hankins, Stephen Gottschalk, Brandon M Triplett, Jason Nathaniel Johnson
Impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell disease. Blood 144 (6) (2024)
Caitlin C Zebley, Dietmar Zehn, Stephen Gottschalk, Hongbo Chi
T cell dysfunction and therapeutic intervention in cancer. Nature immunology 25 (8) (2024)
Swati Naik, Stephen Gottschalk
Is immune escape in the rearview mirror? Blood 143 (2) (2024)
Michael D Keller, Stefan A Schattgen, Shanmuganathan Chandrakasan, Emma Kaitlynn Allen, Mariah A Jensen-Wachspress, Christopher A Lazarski, Muna Qayed, Haili Lang, Patrick J Hanley, Jay Tanna, Sung-Yun Pai, Suhag H Parikh, Seth I Berger, Stephen Gottschalk, Michael A Pulsipher, Paul Glyndwr Thomas, Catherine M Bollard
Secondary bone marrow graft loss after third-party virus-specific T cell infusion: Case report of a rare complication. Nature communications 15 (1) (2024)
Caitlin C Zebley, Dietmar Zehn, Stephen Gottschalk, Hongbo Chi
T cell dysfunction and therapeutic intervention in cancer. Nature immunology (2024)
Timothy I Shaw, Jessica Wagner, Liqing Tian, Elizabeth Wickman, Suresh Poudel, Jian Wang, Robin Paul, Selene C Koo, Meifen Lu, Heather Sheppard, Yiping Fan, Francis H O'Neill, Ching C Lau, Xin Zhou, Jinghui Zhang, Stephen Gottschalk
Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression. Nature communications 15 (1) (2024)
Lindsey J Talbot, Ashley Chabot, Aaron B Ross, Alexandra Beckett, Phuong Nguyen, Andrew M Fleming, Peter J Chockley, Heather S Sheppard, Jian Wang, Stephen Gottschalk, Christopher DeRenzo
Redirecting B7-H3.CAR T cells to Chemokines Expressed in Osteosarcoma Enhances Homing and Antitumor Activity in Preclinical Models. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Timothy I Shaw, Jessica Wagner, Liqing Tian, Elizabeth Wickman, Suresh Poudel, Jian Wang, Robin Paul, Selene C Koo, Meifen Lu, Heather Sheppard, Yiping Fan, Francis H O'Neill, Ching C Lau, Xin Zhou, Jinghui Zhang, Stephen Gottschalk
Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression. Nature communications 15 (1) (2024)
Meenakshi Hegde, Shoba A Navai, Christopher DeRenzo, Sujith K Joseph, Khaled Sanber, Mengfen Wu, Ahmed Z Gad, Katherine A Janeway, Matthew Campbell, Dolores Mullikin, Zeid Nawas, Catherine Robertson, Pretty R Mathew, Huimin Zhang, Birju Mehta, Raksha R Bhat, Angela Major, Ankita Shree, Claudia Gerken, Mamta Kalra, Rikhia Chakraborty, Sachin G Thakkar, Olga Dakhova, Vita S Salsman, Bambi Grilley, Natalia Lapteva, Adrian Gee, Gianpietro Dotti, Riyue Bao, Ahmed Hamed Salem, Nicholas Wang, Malcolm K Brenner, Helen E Heslop, Winfried S Wels, M John Hicks, Stephen Gottschalk, Nabil M Ahmed
Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial. Nature cancer 5 (6) (2024)
Akshay Sharma, Subodh R Selukar, Yu Bi, Anthony Merlocco, Cara E Morin, Chris Goode, Parul Rai, Jeffrey A Towbin, Jane Silva Hankins, Stephen Gottschalk, Brandon M Triplett, Jason Nathaniel Johnson
Impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell disease. Blood 144 (6) (2024)
Meenakshi Hegde, Shoba A Navai, Christopher DeRenzo, Sujith K Joseph, Khaled Sanber, Mengfen Wu, Ahmed Z Gad, Katherine A Janeway, Matthew Campbell, Dolores Mullikin, Zeid Nawas, Catherine Robertson, Pretty R Mathew, Huimin Zhang, Birju Mehta, Raksha R Bhat, Angela Major, Ankita Shree, Claudia Gerken, Mamta Kalra, Rikhia Chakraborty, Sachin G Thakkar, Olga Dakhova, Vita S Salsman, Bambi Grilley, Natalia Lapteva, Adrian Gee, Gianpietro Dotti, Riyue Bao, Ahmed Hamed Salem, Nicholas Wang, Malcolm K Brenner, Helen E Heslop, Winfried S Wels, M John Hicks, Stephen Gottschalk, Nabil M Ahmed
Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial. Nature cancer 5 (6) (2024)
Akshay Sharma, Subodh R Selukar, Yu Bi, Anthony Merlocco, Cara E Morin, Chris Goode, Parul Rai, Jeffrey A Towbin, Jane Silva Hankins, Stephen Gottschalk, Brandon M Triplett, Jason Nathaniel Johnson
Impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell disease. Blood 144 (6) (2024)
Caitlin C Zebley, Dietmar Zehn, Stephen Gottschalk, Hongbo Chi
T cell dysfunction and therapeutic intervention in cancer. Nature immunology 25 (8) (2024)
Meenakshi Hegde, Shoba A Navai, Christopher DeRenzo, Sujith K Joseph, Khaled Sanber, Mengfen Wu, Ahmed Z Gad, Katherine A Janeway, Matthew Campbell, Dolores Mullikin, Zeid Nawas, Catherine Robertson, Pretty R Mathew, Huimin Zhang, Birju Mehta, Raksha R Bhat, Angela Major, Ankita Shree, Claudia Gerken, Mamta Kalra, Rikhia Chakraborty, Sachin G Thakkar, Olga Dakhova, Vita S Salsman, Bambi Grilley, Natalia Lapteva, Adrian Gee, Gianpietro Dotti, Riyue Bao, Ahmed Hamed Salem, Nicholas Wang, Malcolm K Brenner, Helen E Heslop, Winfried S Wels, M John Hicks, Stephen Gottschalk, Nabil M Ahmed
Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial. Nature cancer 5 (6) (2024)
Meenakshi Hegde, Shoba A Navai, Christopher DeRenzo, Sujith K Joseph, Khaled Sanber, Mengfen Wu, Ahmed Z Gad, Katherine A Janeway, Matthew Campbell, Dolores Mullikin, Zeid Nawas, Catherine Robertson, Pretty R Mathew, Huimin Zhang, Birju Mehta, Raksha R Bhat, Angela Major, Ankita Shree, Claudia Gerken, Mamta Kalra, Rikhia Chakraborty, Sachin G Thakkar, Olga Dakhova, Vita S Salsman, Bambi Grilley, Natalia Lapteva, Adrian Gee, Gianpietro Dotti, Riyue Bao, Ahmed Hamed Salem, Nicholas Wang, Malcolm K Brenner, Helen E Heslop, Winfried S Wels, M John Hicks, Stephen Gottschalk, Nabil M Ahmed
Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial. Nature cancer (2024)
Timothy I Shaw, Jessica Wagner, Liqing Tian, Elizabeth Wickman, Suresh Poudel, Jian Wang, Robin Paul, Selene C Koo, Meifen Lu, Heather Sheppard, Yiping Fan, Francis O'Neil, Ching Lau, Xin Zhou, Jinghui Zhang, Stephen Gottschalk
Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression. Research square (2024)
Michael D Keller, Stefan A Schattgen, Shanmuganathan Chandrakasan, Emma Kaitlynn Allen, Mariah A Jensen-Wachspress, Christopher A Lazarski, Muna Qayed, Haili Lang, Patrick J Hanley, Jay Tanna, Sung-Yun Pai, Suhag H Parikh, Seth I Berger, Stephen Gottschalk, Michael A Pulsipher, Paul Glyndwr Thomas, Catherine M Bollard
Secondary bone marrow graft loss after third-party virus-specific T cell infusion: Case report of a rare complication. Nature communications 15 (1) (2024)
Timothy I Shaw, Jessica Wagner, Liqing Tian, Elizabeth Wickman, Suresh Poudel, Jian Wang, Robin Paul, Selene C Koo, Meifen Lu, Heather Sheppard, Yiping Fan, Francis H O'Neill, Ching C Lau, Xin Zhou, Jinghui Zhang, Stephen Gottschalk
Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression. Nature communications 15 (1) (2024)
Swati Naik, Stephen Gottschalk
Is immune escape in the rearview mirror? Blood 143 (2) (2024)
Caitlin C Zebley, Dietmar Zehn, Stephen Gottschalk, Hongbo Chi
T cell dysfunction and therapeutic intervention in cancer. Nature immunology (2024)
Timothy I Shaw, Jessica Wagner, Liqing Tian, Elizabeth Wickman, Suresh Poudel, Jian Wang, Robin Paul, Selene C Koo, Meifen Lu, Heather Sheppard, Yiping Fan, Francis H O'Neill, Ching C Lau, Xin Zhou, Jinghui Zhang, Stephen Gottschalk
Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression. Nature communications 15 (1) (2024)
Timothy I Shaw, Jessica Wagner, Liqing Tian, Elizabeth Wickman, Suresh Poudel, Jian Wang, Robin Paul, Selene C Koo, Meifen Lu, Heather Sheppard, Yiping Fan, Francis O'Neil, Ching C Lau, Xin Zhou, Jinghui Zhang, Stephen Gottschalk
Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression. Research square (2024)
Kristen D Pawlowski, Joseph T Duffy, Stephen Gottschalk, Irina V Balyasnikova
Cytokine Modification of Adoptive Chimeric Antigen Receptor Immunotherapy for Glioblastoma. Cancers 15 (24) (2023)
Sunny Mai, Alan Hodges, Hui-Ming Chen, Jilu Zhang, Yi-Ling Wang, Yongbin Liu, Fumiko Nakatsu, Xiaoxuan Wang, Jing Fang, Yitian Xu, Vitaliy Davidov, Kyeongah Kang, Sai Ravi Pingali, Siddhartha Ganguly, Masataka Suzuki, Marina Y Konopleva, Brooke Prinzing, Youli Zu, Stephen Gottschalk, Yong Lu, Shu-Hsia Chen, Ping-Ying Pan
LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy. Cancer research 83 (24) (2023)
Kristen D Pawlowski, Joseph T Duffy, Stephen Gottschalk, Irina V Balyasnikova
Cytokine Modification of Adoptive Chimeric Antigen Receptor Immunotherapy for Glioblastoma. Cancers 15 (24) (2023)
Sunny Mai, Alan Hodges, Hui-Ming Chen, Jilu Zhang, Yi-Ling Wang, Yongbin Liu, Fumiko Nakatsu, Xiaoxuan Wang, Jing Fang, Yitian Xu, Vitaliy Davidov, Kyeongah Kang, Sai Ravi Pingali, Siddhartha Ganguly, Masataka Suzuki, Marina Y Konopleva, Brooke Prinzing, Youli Zu, Stephen Gottschalk, Yong Lu, Shu-Hsia Chen, Ping-Ying Pan
LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy. Cancer research 83 (24) (2023)
Koon-Kiu Yan, Jose Condori, Zhijun Ma, Jean-Yves Metais, Bensheng Ju, Liang Ding, Yogesh Dhungana, Lance E Palmer, Deanna M Langfitt, Francesca Ferrara, Robert E Throm, Hao Shi, Isabel Risch, Sheetal Bhatara, Bridget Shaner, Timothy D Lockey, Aimee C Talleur, John Easton, Michael M Meagher, Jennifer M Puck, Morton J Cowan, Sheng Zhou, Ewelina Mamcarz, Stephen Gottschalk, Jiyang Yu
Integrome signatures of lentiviral gene therapy for SCID-X1 patients. Science advances 9 (40) (2023)
Dalia Haydar, Jorge Ibañez-Vega, Jeremy Crawford, Ching-Heng Chou, Cliff Guy, Michaela Meehl, Zhongzhen Yi, Deanna M Langfitt, Peter Vogel, Christopher DeRenzo, Stephen Gottschalk, Martine F Roussel, Paul Glyndwr Thomas, Giedre Krenciute
CAR T-cell design dependent remodeling of the brain tumor immune microenvironment identify macrophages as key players that inhibit or promote anti-tumor activity. Research square (2023)
Dalia Haydar, Jorge Ibañez-Vega, Jeremy Chase Crawford, Ching-Heng Chou, Clifford S Guy, Michaela Meehl, Zhongzhen Yi, Scott Perry, Jonathan Laxton, Trevor Cunningham, Deanna M Langfitt, Peter Vogel, Christopher DeRenzo, Stephen Gottschalk, Martine F Roussel, Paul Glyndwr Thomas, Giedre Krenciute
CAR T-cell design-dependent remodeling of the brain tumor-immune microenvironment modulates tumor-associated macrophages and anti-glioma activity. Cancer research communications (2023)
Caleb A Lareau, Yajie Yin, Katie Maurer, Katalin D Sandor, Bence Daniel, Garima Yagnik, José Peña, Jeremy Chase Crawford, Stephan Mielke, Jacob C Gutierrez, Nicholas J Haradhvala, Janice M Riberdy, Tsion Abay, Robert R Stickels, Jeffrey M Verboon, Vincent Liu, Frank A Buquicchio, Fangyi Wang, Jackson Southard, Ren Song, Wenjing Li, Aastha Shrestha, Laxmi Parida, Gad A Getz, Marcela V Maus, Shuqiang Li, Alison Moore, Zachary J Roberts, Leif S Ludwig, Aimee C Talleur, Paul Glyndwr Thomas, Houman Dehghani, Thomas Pertel, Anshul Kundaje, Stephen Gottschalk, Theodore L Roth, Marie José Kersten, Catherine J Wu, Robbie G Majzner, Ansuman T Satpathy
Latent human herpesvirus 6 is reactivated in CAR T cells. Nature (2023)
Rebecca Epperly, Barry L Shulkin, Asim K Bag, Cheng Cheng, Hiroto Inaba, John T Lucas, Swati Naik, Brandon M Triplett, Stephen Gottschalk, Aimee C Talleur
CD19-CAR T-Cell Therapy Demonstrates Activity Against Extramedullary Disease in Pediatric Patients with B-ALL. Blood advances (2023)
Sunny Mai, Alan Hodges, Hui-Ming Chen, Jilu Zhang, Yi-Ling Wang, Yongbin Liu, Fumiko Nakatsu, Xiaoxuan Wang, Jing Fang, Yitian Xu, Vitaliy Davidov, Kyeongah Kang, Sai Ravi Pingali, Siddhartha Ganguly, Masataka Suzuki, Marina Y Konopleva, Brooke Prinzing, Youli Zu, Stephen Gottschalk, Yong Lu, Shu-Hsia Chen, Ping-Ying Pan
LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy. Cancer research 83 (24) (2023)
Alex N Beckett, Peter J Chockley, Shondra M Pruett-Miller, Phuong Nguyen, Peter Vogel, Heather Sheppard, Giedre Krenciute, Stephen Gottschalk, Christopher DeRenzo
CD47 expression is critical for CAR T-cell survival in vivo. Journal for immunotherapy of cancer 11 (3) (2023)
Peter J Chockley, Jorge Ibañez-Vega, Giedre Krenciute, Lindsay J Talbot, Stephen Gottschalk
Synapse-tuned CARs enhance immune cell anti-tumor activity. Nature biotechnology (2023)
Matthew Bell, Shannon Lange, Besian I Sejdiu, Jorge Ibañez-Vega, Hao Shi, Xiang Sun, Xiaoxi Meng, Phuong Nguyen, Morgan Sutton, Jessica Wagner, Anil Kc, Deanna M Langfitt, Sagar L Patil, Haiyan Tan, Ram Vinay Pandey, Yuxin Li, Zuo-Fei Yuan, Alejandro Allo Anido, Mitchell Ho, Heather Sheppard, Peter Vogel, Jiyang Yu, Junmin Peng, Hongbo Chi, M Madan Babu, Giedre Krenciute, Stephen Gottschalk
Modular chimeric cytokine receptors with leucine zippers enhance the antitumour activity of CAR T cells via JAK/STAT signalling. Nature biomedical engineering (2023)
Sunny Mai, Alan Hodges, Hui-Ming Chen, Jilu Zhang, Yi-Ling Wang, Yongbin Liu, Fumiko Nakatsu, Xiaoxuan Wang, Jing Fang, Yitian Xu, Vitaliy Davidov, Kyeongah Kang, Sai Ravi Pingali, Siddhartha Ganguly, Masataka Suzuki, Marina Y Konopleva, Brooke Prinzing, Youli Zu, Stephen Gottschalk, Yong Lu, Shu-Hsia Chen, Ping-Ying Pan
LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy. Cancer research 83 (24) (2023)
Kristen D Pawlowski, Joseph T Duffy, Stephen Gottschalk, Irina V Balyasnikova
Cytokine Modification of Adoptive Chimeric Antigen Receptor Immunotherapy for Glioblastoma. Cancers 15 (24) (2023)
David H M Steffin, Ibrahim N. Muhsen, LaQuisa C Hill, Carlos Almeida Ramos, Nabil M Ahmed, Meenakshi Hegde, Nicholas Wang, Mengfen Wu, Stephen Gottschalk, Sarah B Whittle, Premal D Lulla, Maksim Mamonkin, Bilal Omer, Rayne H Rouce, Andras A Heczey, Leonid S Metelitsa, Bambi J Grilley, Catherine Robertson, Virginia Torrano, Natalia Lapteva, Adrian P Gee, Cliona M Rooney, Malcolm K Brenner, Helen E Heslop
Long-term follow-up for the development of subsequent malignancies in patients treated with genetically modified IECs. Blood 140 (1) (2022)
Swati Naik, Spyridoula Vasileiou, Ifigeneia Tzannou, Manik Kuvalekar, Ayumi Watanabe, Catherine Robertson, Natalia Lapteva, Nicholas Wang, Mengfen Wu, Bambi Grilley, George Carrum, Rammurti T Kamble, LaQuisa C Hill, Robert A Krance, Caridad Martinez, Priti Tewari, Bilal Omer, Stephen Gottschalk, Helen E Heslop, Malcom K Brenner, Cliona M Rooney, Juan F Vera, Ann M Leen, Premal D Lulla
Donor-derived multiple leukemia antigen-specific T-cell therapy to prevent relapse after transplant in patients with ALL. Blood 139 (17) (2022)
Claudia Manuela Arnone, Vinicia Assunta Polito, Angela Mastronuzzi, Andrea Carai, Francesca Camassei Diomedi, Laura Antonucci, Lucia Lisa Petrilli, Maria Vinci, Francesco Ferrari, Elisa Salviato, Marco Scarsella, Cristiano De Stefanis, Gerrit Weber, Concetta Quintarelli, Biagio De Angelis, Malcolm K Brenner, Stephen Gottschalk, Valentina Hoyos, Franco Locatelli, Ignazio Caruana, Francesca Del Bufalo
Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas. Journal for immunotherapy of cancer 9 (5) (2022)
Abdullah Freiwan, Jaquelyn T Zoine, Jeremy Chase Crawford, Abishek Vaidya, Stefan A Schattgen, Jacquelyn Myers, Sagar L Patil, Mahsa Khanlari, Hiroto Inaba, Jeffery M Klco, Charles G Mullighan, Giedre Krenciute, Peter J Chockley, Swati Naik, Deanna Langfitt, Maksim Mamonkin, Esther A Obeng, Paul Glyndwr Thomas, Stephen Gottschalk, Mireya Paulina Velasquez
Engineering Naturally Occurring CD7 Negative T Cells for the Immunotherapy of Hematological Malignancies. Blood (2022)
Young-In Kim-Hoehamer, Janice M Riberdy, Fei Zheng, Jeoungeun J Park, Na Shang, Jean-Yves Metais, Timothy D Lockey, Catherine Willis, Salem Akel, Jennifer Moore, Michael M Meagher, M Paulina Velasquez, Brandon M Triplett, Aimee C Talleur, Stephen Gottschalk, Sheng Zhou
Development of a cGMP-compliant process to manufacture donor-derived, CD45RA-depleted memory CD19-CAR T cells. Gene therapy (2022)
Taylor L Wilson, Hyunjin Kim, Ching-Heng Chou, Deanna M Langfitt, Robert C Mettelman, Anastasia A Minervina, Emma Kaitlynn Allen, Jean-Yves Metais, Mikhail V Pogorelyy, Janice M Riberdy, Mireya Paulina Velasquez, Pratibha Kottapalli, Sanchit Trivedi, Scott R Olsen, Timothy D Lockey, Catherine Willis, Michael M Meagher, Brandon M Triplett, Aimee C Talleur, Stephen Gottschalk, Jeremy Chase Crawford, Paul Glyndwr Thomas
Common Trajectories of Highly Effective CD19-Specific CAR T Cells Identified by Endogenous T-cell Receptor Lineages. Cancer discovery 12 (9) (2022)
Aimee C Talleur, Amr Qudeimat, Jean-Yves Metais, Deanna Langfitt, Ewelina Mamcarz, Jeremy Chase Crawford, Sujuan Huang, Cheng Cheng, Caitlin Hurley, Renee Madden, Akshay Sharma, Ali Suliman, Ashok Srinivasan, Mireya Paulina Velasquez, Esther A Obeng, Catherine Willis, Salem Akel, Seth E Karol, Hiroto Inaba, Allison Bragg, Wenting Zheng, Sheng M Zhou, Sarah Schell, MaCal Tuggle-Brown, David Cullins, Sagar L Patil, Ying Li, Paul Glyndwr Thomas, Caitlin Zebley, Benjamin Youngblood, Ching-Hon Pui, Timothy Lockey, Terrence L Geiger, Michael M Meagher, Brandon M Triplett, Stephen Gottschalk
Preferential expansion of CD8+ CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL. Blood advances 6 (21) (2022)
Thomas Pfeiffer, Ying Li, Emily Ashcraft, Seth E Karol, Jeffrey E Rubnitz, Rebecca Epperly, Renee Madden, Ewelina Mamcarz, Esther A Obeng, Amr Qudeimat, Akshay Sharma, Ashok Srinivasan, Ali Y Suliman, Aimee C Talleur, Mireya Paulina Velasquez, Stephen Gottschalk, Brandon M Triplett, Swati Naik
Venetoclax-based therapy as a bridge to allogeneic hematopoietic cell transplantation in children with relapsed/refractory AML. Bone marrow transplantation (2022)
Shihong Zhang, R Graeme Black, Karan Kohli, Brian J Hayes, Cassandra Miller, Amanda L Koehne, Brett A Schroeder, Kraig Abrams, Brian C Schulte, Borislav A Alexiev, Amy B Heimberger, Ali Zhang, Weiqing Jing, Juliana Chi Kei Ng, Himaly Shinglot, Bernard Séguin, Alexander I Salter, Stanley R Riddell, Michael C Jensen, Stephen Gottschalk, Peter F Moore, Beverly Torok-Storb, Seth M Pollack
B7-H3 Specific CAR T Cells for the Naturally Occurring, Spontaneous Canine Sarcoma Model. Molecular cancer therapeutics 21 (6) (2022)
Julia Carnevale, Eric Shifrut, Nupura Kale, William A Nyberg, Franziska Blaeschke, Yan Yi Chen, Zhongmei Li, Sagar P Bapat, Morgan E Diolati, Patrick C O'Leary, Shane Vedova, Julia A Belk, Bence Daniel, Theodore L Roth, Stefanie Bachl, Alejandro Allo Anido, Brooke Prinzing, Jorge Ibañez-Vega, Shannon Lange, Dalia Haydar, Marie Luetke-Eversloh, Maelys Born-Bony, Bindu Hegde, Scott C Kogan, Tobias Feuchtinger, Hideho Okada, Ansuman T Satpathy, Kevin Shannon, Stephen Gottschalk, Justin Eyquem, Giedre Krenciute, Alan Ashworth, Alexander Marson
RASA2 ablation in T cells boosts antigen sensitivity and long-term function. Nature 609 (7925) (2022)
Bilal Omer, Mara G Cardenas, Thomas Pfeiffer, Rachel Daum, Mai Huynh, Sandhya Sharma, Nazila Nouraee, Cicilyn Xie, Candise Tat, Silvana Perconti, Stacey Van Pelt, Lauren Scherer, Christopher DeRenzo, Thomas Shum, Stephen Gottschalk, Caroline Arber, Cliona M Rooney
A Costimulatory CAR Improves TCR-based Cancer Immunotherapy. Cancer immunology research 10 (4) (2022)
Nikhil Hebbar, Rebecca Epperly, Abishek Vaidya, Unmesha Thanekar, Sarah E Moore, Masayuki Umeda, Jing Ma, Sagar L Patil, Deanna M Langfitt, Sujuan Huang, Cheng Cheng, Jeffery M Klco, Stephen Gottschalk, Mireya Paulina Velasquez
CAR T cells redirected to cell surface GRP78 display robust anti-acute myeloid leukemia activity and do not target hematopoietic progenitor cells. Nature communications 13 (1) (2022)
Brooke Prinzing, Caitlin C Zebley, Christopher T Petersen, Yiping Fan, Alejandro Allo Anido, Zhongzhen Yi, Phuong Nguyen, Haley Houke, Matthew Bell, Dalia Haydar, Charmaine Brown, Shannon K Boi, Shanta Alli, Jeremy Chase Crawford, Janice M Riberdy, Jeoungeun J Park, Sheng Zhou, Mireya Paulina Velasquez, Christopher DeRenzo, Cicera R Lazzarotto, Shengdar Q Tsai, Peter Vogel, Shondra M Pruett-Miller, Deanna M Langfitt, Stephen Gottschalk, Benjamin A Youngblood, Giedre Krenciute
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Science translational medicine 13 (620) (2021)
Saisha A Nalawade, Paul Shafer, Pradip Bajgain, Mary K McKenna, Arushana Ali, Lauren Kelly, Jarrett Joubert, Stephen Gottschalk, Norihiro Watanabe, Ann Leen, Robin Parihar, Juan Fernando Vera Valdes, Valentina Hoyos
Selectively targeting myeloid-derived suppressor cells through TRAIL receptor 2 to enhance the efficacy of CAR T cell therapy for treatment of breast cancer. Journal for immunotherapy of cancer 9 (11) (2021)
Matthew H Wilson, Stephen Gottschalk
Expect the unexpected: piggyBac and lymphoma. Blood 138 (16) (2021)
Shannon Lange, Laurens G L Sand, Matthew Bell, Sagar L Patil, Deanna Langfitt, Stephen Gottschalk
A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function. Cancer discovery 11 (7) (2021)
Premal D Lulla, Swati Naik, Spyridoula Vasileiou, Ifigeneia Tzannou, Ayumi Watanabe, Manik Kuvalekar, Suhasini Lulla, George Carrum, Carlos Almeida Ramos, Rammurti Kamble, LaQuisa C Hill, Jasleen Randhawa, Stephen Gottschalk, Robert Krance, Nicholas Wang, Mengfen Wu, Catherine Robertson, Adrian P Gee, Betty Chung, Bambi Grilley, Malcolm K Brenner, Helen E Heslop, Juan F Vera, Ann M Leen
Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS after allogeneic transplant. Blood 137 (19) (2021)
M Paulina Velasquez, Stephen Gottschalk
Employing Synthetic T-cell Biology to Target AML without On-Target/Off-Cancer Toxicity. Blood cancer discovery 2 (6) (2021)
Tim Sauer, Kathan Parikh, Sandhya Sharma, Bilal Omer, David Sedloev, Qian Chen, Linus Angenendt, Christoph Schliemann, Michael Schmitt, Carsten Müller-Tidow, Stephen Gottschalk, Cliona M Rooney
CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity. Blood 138 (4) (2021)
Akshay Sharma, Ying Li, Sujuan Huang, Aimee C Talleur, Ali Y Suliman, Amr Qudeimat, Ashok Srinivasan, Ewelina Mamcarz, Renee Madden, Cheng Cheng, Stephen Gottschalk, Brandon M Triplett
Outcomes of pediatric patients who relapse after first HCT for acute leukemia or MDS. Bone marrow transplantation 56 (8) (2021)
Jessica Wagner, Elizabeth Wickman, Timothy I Shaw, Alejandro Allo Anido, Deanna Langfitt, Jinghui Zhang, Shaina N Porter, Shondra M Pruett-Miller, Heather Tillman, Giedre Krenciute, Stephen Gottschalk
Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin. Cancer immunology research 9 (3) (2020)
Ifigeneia Tzannou, Ayumi Watanabe, Swati Naik, Rachel Daum, Manik Kuvalekar, Kathryn S Leung, Caridad Martinez, Ghadir Sasa, Mengfen Wu, Adrian P Gee, Robert A Krance, Stephen Gottschalk, Helen E Heslop, Bilal Omer
"Mini" bank of only 8 donors supplies CMV-directed T cells to diverse recipients. Blood advances 3 (17) (2020)
Meenakshi Hegde, Sujith K Joseph, Farzana D Pashankar, Christopher DeRenzo, Khaled Sanber, Shoba A Navai, Tiara T Byrd, John Hicks, Mina L Xu, Claudia Gerken, Mamta Kalra, Catherine Robertson, Huimin Zhang, Ankita Shree, Birju Mehta, Olga Dakhova, Vita S Salsman, Bambi Grilley, Adrian Gee, Gianpietro Dotti, Helen E Heslop, Malcolm K Brenner, Winfried S Wels, Stephen Gottschalk, Nabil M Ahmed
Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma. Nature communications 11 (1) (2020)
Kenneth Hsu, Shiloh Middlemiss, Federica Saletta, Stephen Gottschalk, Geoffrey B McCowage, Belinda Kramer
Chimeric Antigen Receptor-modified T cells targeting EphA2 for the immunotherapy of paediatric bone tumours. Cancer gene therapy 28 (3-4) (2020)
Melinda Mata, Stephen Gottschalk
Engineering for Success: Approaches to Improve Chimeric Antigen Receptor T Cell Therapy for Solid Tumors. Drugs 79 (4) (2019)
Kota Iwahori, Yasushi Shintani, Soichiro Funaki, Yoko Yamamoto, Mitsunobu Matsumoto, Tetsuya Yoshida, Akiko Morimoto-Okazawa, Atsunari Kawashima, Eiichi Sato, Stephen Gottschalk, Meinoshin Okumura, Atsushi Kumanogoh, Hisashi Wada
Peripheral T cell cytotoxicity predicts T cell function in the tumor microenvironment. Scientific reports 9 (1) (2019)
Ewelina Mamcarz, Renee Madden, Amr Qudeimat, Ashok Srinivasan, Aimee C Talleur, Akshay Sharma, Ali Suliman, Gabriela Maron, Anusha Sunkara, Guolian Kang, Wing Leung, Stephen Gottschalk, Brandon M Triplett
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