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Evaluating the population impact of hepatitis C direct acting antiviral treatment as prevention for people who inject drugs (EPIToPe) - a natural experiment (protocol).

Matthew HickmanJohn F DillonLawrie ElliottDaniela De AngelisPeter VickermanGraham FosterPeter DonnanAnn EriksenPaul FlowersDavid GoldbergWilliam HollingworthSamreen IjazDavid LiddellSema MandalNatasha MartinLewis J Z BeerKate DrysdaleHannah FraserRachel GlassLesley GrahamRory N GunsonEmma HamiltonHelen HarrisMagdalena HarrisRoss HarrisEllen HeinsbroekVivian HopeJeremy HorwoodSarah Karen InglisHamish InnesAthene LaneJade MeadowsAndrew McAuleyChris MetcalfeStephanie MigchelsenAlex MurrayGareth MyringNorah E PalmateerAnne PresanisAndrew RadleyMary RamsayPantelis SamartsidisRuth SimmonsKaty SinkaGabriele VojtZoe WardDavid WhiteleyAlan YeungSharon J Hutchinson
Published in: BMJ open (2019)
Extending HCV community care pathways is covered by ethics (ERADICATE C, ISRCTN27564683, Super DOT C Trial clinicaltrials.gov: NCT02706223). Ethical approval for extra data collection from patients including health utilities and qualitative interviews has been granted (REC ref: 18/ES/0128) and ISCRCTN registration has been completed (ISRCTN72038467). Our findings will have direct National Health Service and patient relevance; informing prioritisation given to early HCV treatment for PWID. We will present findings to practitioners and policymakers, and support design of an evaluation of HCV TasP in England.
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