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Quantification of the Time Course of CYP3A Inhibition, Activation, and Induction Using a Population Pharmacokinetic Model of Microdosed Midazolam Continuous Infusion.

Yomna M NassarNicolas HohmannRobin MicheletKatharina GottwaltAndreas D MeidJürgen BurhenneWilhelm HuisingaWalter Emil HaefeliGerd MikusCharlotte Kloft
Published in: Clinical pharmacokinetics (2022)
The trial was registered at the European Union Drug Regulating Authorities for Clinical Trials (EudraCT-No. 2013-004869-14).
Keyphrases
  • clinical trial
  • phase ii
  • phase iii
  • study protocol
  • low dose
  • open label
  • double blind
  • adverse drug
  • placebo controlled