Wilhelm Huisinga

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 27

Top Topics

Direct Oral Anticoagulants

Tyrosine Kinase

Fluorescence Imaging

Top Venues

PLoS computational biology

CPT: pharmacometrics & systems pharmacology

Clinical pharmacology and therapeutics

This page only lists publications with an associated author ORCID identifier.

Publications

Jane Knöchel, Charlotte Kloft, Wilhelm Huisinga
Index analysis: An approach to understand signal transduction with application to the EGFR signalling pathway. PLoS computational biology 20 (2) (2024)
Daniel Schindler, Ted Moldenhawer, Carsten Beta, Wilhelm Huisinga, Matthias Holschneider
Three-component contour dynamics model to simulate and analyze amoeboid cell motility in two dimensions. PloS one 19 (1) (2024)
Jane Knöchel, Charlotte Kloft, Wilhelm Huisinga
Index analysis: An approach to understand signal transduction with application to the EGFR signalling pathway. PLoS computational biology 20 (2) (2024)
Jane Knöchel, Charlotte Kloft, Wilhelm Huisinga
Index analysis: An approach to understand signal transduction with application to the EGFR signalling pathway. PLoS computational biology 20 (2) (2024)
Daniel Seeler, Nastasja Grdseloff, Claudia Jasmin Rödel, Charlotte Kloft, Salim Abdelilah-Seyfried, Wilhelm Huisinga
Novel mathematical approach to accurately quantify 3D endothelial cell morphology and vessel geometry based on fluorescently marked endothelial cell contours: Application to the dorsal aorta of wild-type and Endoglin-deficient zebrafish embryos. PLoS computational biology 20 (8) (2024)
Undine Falkenhagen, Larisa H Cavallari, Julio D Duarte, Charlotte Kloft, Stephan Schmidt, Wilhelm Huisinga
Leveraging QSP Models for MIPD: A Case Study for Warfarin/INR. Clinical pharmacology and therapeutics (2024)
Undine Falkenhagen, Larisa H Cavallari, Julio D Duarte, Charlotte Kloft, Stephan Schmidt, Wilhelm Huisinga
Leveraging QSP Models for MIPD: A Case Study for Warfarin/INR. Clinical pharmacology and therapeutics 116 (3) (2024)
Jane Knöchel, Charlotte Kloft, Wilhelm Huisinga
Index analysis: An approach to understand signal transduction with application to the EGFR signalling pathway. PLoS computational biology 20 (2) (2024)
Daniel Schindler, Ted Moldenhawer, Carsten Beta, Wilhelm Huisinga, Matthias Holschneider
Three-component contour dynamics model to simulate and analyze amoeboid cell motility in two dimensions. PloS one 19 (1) (2024)
Daniel Schindler, Ted Moldenhawer, Carsten Beta, Wilhelm Huisinga, Matthias Holschneider
Three-component contour dynamics model to simulate and analyze amoeboid cell motility in two dimensions. PloS one 19 (1) (2024)
Jane Knöchel, Charlotte Kloft, Wilhelm Huisinga
Index analysis: An approach to understand signal transduction with application to the EGFR signalling pathway. PLoS computational biology 20 (2) (2024)
Davide Bindellini, Robin Michelet, Linda B S Aulin, Johanna Melin, Uta Neumann, Oliver Blankenstein, Wilhelm Huisinga, Martin J Whitaker, Richard J Ross, Charlotte Kloft
A quantitative modeling framework to understand the physiology of the hypothalamic-pituitary-adrenal axis and interaction with cortisol replacement therapy. Journal of pharmacokinetics and pharmacodynamics (2024)
Sabine Stübler, Charlotte Kloft, Wilhelm Huisinga
Cell-level systems biology model to study inflammatory bowel diseases and their treatment options. CPT: pharmacometrics & systems pharmacology (2023)
Franziska Kluwe, Robin Michelet, Wilhelm Huisinga, Markus Zeitlinger, Gerd Mikus, Charlotte Kloft
Towards Model-Informed Precision Dosing of Voriconazole: Challenging Published Voriconazole Nonlinear Mixed-Effects Models with Real-World Clinical Data. Clinical pharmacokinetics (2023)
Viktoria Stachanow, Uta Neumann, Oliver Blankenstein, Nele Alder-Baerens, Davide Bindellini, Peter Hindmarsh, Richard J Ross, Martin J Whitaker, Johanna Melin, Wilhelm Huisinga, Robin Michelet, Charlotte Kloft
Model-Informed Target Morning 17α-Hydroxyprogesterone Concentrations in Dried Blood Spots for Pediatric Congenital Adrenal Hyperplasia Patients. Pharmaceuticals (Basel, Switzerland) 16 (3) (2023)
Francis Williams Ojara, Andrea Henrich, Nicolas Frances, Yomna M Nassar, Wilhelm Huisinga, Niklas Hartung, Kimberly Geiger, Stefan Holdenrieder, Markus Joerger, Charlotte Kloft
A prognostic baseline blood biomarker and tumor growth kinetics integrated model in paclitaxel/platinum treated advanced non-small cell lung cancer patients. CPT: pharmacometrics & systems pharmacology (2023)
Viktoria Stachanow, Uta Neumann, Oliver Blankenstein, Nele Alder-Baerens, Davide Bindellini, Peter Hindmarsh, Richard J Ross, Martin J Whitaker, Johanna Melin, Wilhelm Huisinga, Robin Michelet, Charlotte Kloft
Model-Informed Target Morning 17α-Hydroxyprogesterone Concentrations in Dried Blood Spots for Pediatric Congenital Adrenal Hyperplasia Patients. Pharmaceuticals (Basel, Switzerland) 16 (3) (2023)
Francis Williams Ojara, Andrea Henrich, Nicolas Frances, Yomna M Nassar, Wilhelm Huisinga, Niklas Hartung, Kimberly Geiger, Stefan Holdenrieder, Markus Joerger, Charlotte Kloft
A prognostic baseline blood biomarker and tumor growth kinetics integrated model in paclitaxel/platinum treated advanced non-small cell lung cancer patients. CPT: pharmacometrics & systems pharmacology (2023)
Undine Falkenhagen, Jane Knöchel, Charlotte Kloft, Wilhelm Huisinga
Deriving mechanism-based pharmacodynamic models by reducing quantitative systems pharmacology models: An application to warfarin. CPT: pharmacometrics & systems pharmacology (2023)
Viktoria Stachanow, Uta Neumann, Oliver Blankenstein, Nele Alder-Baerens, Davide Bindellini, Peter Hindmarsh, Richard J Ross, Martin J Whitaker, Johanna Melin, Wilhelm Huisinga, Robin Michelet, Charlotte Kloft
Model-Informed Target Morning 17α-Hydroxyprogesterone Concentrations in Dried Blood Spots for Pediatric Congenital Adrenal Hyperplasia Patients. Pharmaceuticals (Basel, Switzerland) 16 (3) (2023)
Yomna M Nassar, Francis Williams Ojara, Alejandro Pérez-Pitarch, Kimberly Geiger, Wilhelm Huisinga, Niklas Hartung, Robin Michelet, Stefan Holdenrieder, Markus Joerger, Charlotte Kloft
C-Reactive Protein as an Early Predictor of Efficacy in Advanced Non-Small-Cell Lung Cancer Patients: A Tumor Dynamics-Biomarker Modeling Framework. Cancers 15 (22) (2023)
Sabine Stübler, Charlotte Kloft, Wilhelm Huisinga
Cell-level systems biology model to study inflammatory bowel diseases and their treatment options. CPT: pharmacometrics & systems pharmacology (2023)
Yomna M Nassar, Nicolas Hohmann, Robin Michelet, Katharina Gottwalt, Andreas D Meid, Jürgen Burhenne, Wilhelm Huisinga, Walter Emil Haefeli, Gerd Mikus, Charlotte Kloft
Quantification of the Time Course of CYP3A Inhibition, Activation, and Induction Using a Population Pharmacokinetic Model of Microdosed Midazolam Continuous Infusion. Clinical pharmacokinetics 61 (11) (2022)
Christoph Hethey, Niklas Hartung, Gaby Wangorsch, Karin Weisser, Wilhelm Huisinga
Physiology-based toxicokinetic modelling of aluminium in rat and man. Archives of toxicology 95 (9) (2021)
David Busse, Philipp Simon, David Petroff, Christoph Dorn, Lisa Schmitt, Davide Bindellini, Alexander Kratzer, Arne Dietrich, Markus Zeitlinger, Wilhelm Huisinga, Robin Michelet, Hermann Wrigge, Charlotte Kloft
Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics. Pharmaceutics 13 (9) (2021)
David Busse, Jens Markus Borghardt, David Petroff, Alice Pevzner, Christoph Dorn, Nahed El-Najjar, Wilhelm Huisinga, Hermann Wrigge, Philipp Simon, Charlotte Kloft
Evaluating prediction methods for glomerular filtration to optimise drug doses in obese and nonobese patients. British journal of clinical pharmacology (2021)
Franziska Kluwe, Robin Michelet, Anna M Mc Laughlin, Corinna Maier, Lena Klopp-Schulze, Madelé van Dyk, Gerd Mikus, Wilhelm Huisinga, Charlotte Kloft
Perspectives on Model-Informed Precision Dosing in the Digital Health Era: Challenges, Opportunities, and Recommendations. Clinical pharmacology and therapeutics 109 (1) (2020)