Alterations in Baroreflex Sensitivity and Blood Pressure Variability Following Sport-Related Concussion.
Chase J EllingsonJyotpal SinghCody A EllingsonLuke W SirantGregory P KrätzigKim D DorschJaroslaw PiskorskiJ Patrick NearyPublished in: Life (Basel, Switzerland) (2022)
Current methods to diagnose concussions are subjective and difficult to confirm. A variety of physiological biomarkers have been reported, but with conflicting results. This study assessed heart rate variability (HRV), spontaneous baroreflex sensitivity (BRS), and systolic blood pressure variability (BPV) in concussed athletes. The assessment consisted of a 5-min seated rest followed by a 5-min (0.1 Hz) controlled breathing protocol. Thirty participants completed baseline assessments. The protocol was repeated during the post-injury acute phase (days one to five). Total ( p = 0.02) and low-frequency ( p = 0.009) BPV spectral power were significantly decreased during the acute phase of concussion. BRS down-sequence ( p = 0.036) and up-sequence ( p = 0.05) were significantly increased in the acute phase of concussion, with a trend towards an increased BRS pooled ( p = 0.06). Significant decreases in HRV were also found. Acute concussion resulted in altered BRS and BPV dynamics compared to baseline. These findings highlight objective physiological parameters that could aid concussion diagnosis and return-to-play protocols.
Keyphrases
- blood pressure
- mild traumatic brain injury
- heart rate variability
- heart rate
- high school
- randomized controlled trial
- hypertensive patients
- heart failure
- left ventricular
- liver failure
- clinical trial
- optical coherence tomography
- intensive care unit
- physical activity
- type diabetes
- skeletal muscle
- adipose tissue
- computed tomography
- amino acid
- atrial fibrillation
- magnetic resonance
- extracorporeal membrane oxygenation
- hepatitis b virus
- open label
- phase iii
- contrast enhanced
- anterior cruciate ligament