An insight into the diagnostic and prognostic value of HOX A13's expression in non-muscle invasive bladder cancer.

Nouha Setti Boubaker Aymone Gurtner Nesrine Trabelsi Isabella Manni Ahlem Blel Ahmed SaadiMarouene ChakrounZeineb NaimiSelim ZaghbibMeriam KsontiniKhedija Meddeb Soumaya Rammeh Haroun Ayed Mohamed Chebil Giulia Piaggio Slah Ouerhani

Published in: Journal of clinical laboratory analysis (2022)

The deregulation of HOX A13 is not associated with the prognosis of BCa. It seems to be rather implicated in the early initiation of urothelial tumorigenesis and thus may serve as a diagnostic marker in patients with NMIBC. Further experimentations on larger validation sets are mandatory.

Keyphrases

muscle invasive bladder cancer
poor prognosis
high grade
binding protein
urinary tract
clinical evaluation