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Pegylated-l-asparaginase therapy for feline large cell lymphoma: 82 cases (2017-2020).

Céline Anne BikBart Eduardus Wilhelmus RuijterLindsay Van den BosscheErik TeskeStijn Jm NiessenYaiza Forcada
Published in: Journal of feline medicine and surgery (2023)
Based on the response rate and median disease-free period, treatment with pegylated-l-asparaginase is inferior when compared with historical chemotherapy protocols. However, some cats demonstrated an exceptional long disease-free period. Therefore, pegylated-l-asparaginase could be offered as an alternative to corticosteroid therapy alone. Further studies are needed to evaluate the additional benefit over palliative corticosteroid monotherapy.
Keyphrases
  • combination therapy
  • cell therapy
  • single cell
  • diffuse large b cell lymphoma
  • recombinant human
  • randomized controlled trial
  • open label
  • radiation therapy
  • advanced cancer