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Efficacy and safety of a morning injection of insulin glargine 300 units/mL versus insulin glargine 100 units/mL in adult patients with type 1 diabetes: A multicentre, randomized controlled trial using continuous glucose monitoring.

Jeremy H PettusJasvinder GillSachin ParanjapeJohn StewartShilpy MallaSteven V EdelmanRichard M BergenstalBruce Bode
Published in: Diabetes, obesity & metabolism (2019)
Time in range and glycaemic variability were similar for Gla-300 and Gla-100 recipients at the end of study in the mITT population of relatively well-controlled patients with T1D. In patients with end-of-study HbA1c <7.5%, exploratory analyses suggested that Gla-300 provided improvements in time in range compared with Gla-100.
Keyphrases
  • type diabetes
  • randomized controlled trial
  • glycemic control
  • study protocol
  • clinical trial
  • systematic review
  • cross sectional
  • adipose tissue
  • metabolic syndrome
  • young adults
  • weight loss