Effects of physical activity on depressive symptoms during breast cancer survivorship: a meta-analysis of randomised control trials.
Efrossini D PatsouGeorgios D AlexiasFotios G AnagnostopoulosMichalis V KaramouzisPublished in: ESMO open (2017)
BackgroundBreast cancer is one of the most common cancers affecting women worldwide, and depressive symptoms are disturbing side effects of cancer diagnosis and treatment. Physical activity and exercise have emerged as an alternative treatment in handling psychological distress throughout breast cancer survivorship. AimThe aim of this review was to present the results of (1) physical activity and (2) exercise interventions in terms of type and duration regarding depressive symptoms among breast cancer survivors during and after treatment. The hypothesis was that cancer survivors who are engaged with physical activity will demonstrate statistically significant lower levels of depressive symptoms when compared with non-exercising control groups. MethodsWe searched PubMed, Elsevier and Google Scholar for recent articles published between January 2011 and November 2016. Fourteen randomised control trials with 1701 patients in total were assessed. ResultsSignificant differences in levels were found between exercise intervention groups and control groups, while moderate aerobic exercise interventions with an optimal duration of ≥135 min for up to 12 weeks are significantly more beneficial in depressive symptoms when it comes to patients under treatment than resistance, aerobicandresistance training and yoga interventions. ConclusionsIt is concluded that when progressive exercise programmes are prescribed according to the individual needs, capabilities and preferences of breast cancer survivors, they offer a valid alternative to depression mood management throughout the course of survivorship.
Keyphrases
- physical activity
- depressive symptoms
- sleep quality
- childhood cancer
- end stage renal disease
- social support
- high intensity
- body mass index
- chronic kidney disease
- clinical trial
- newly diagnosed
- ejection fraction
- peritoneal dialysis
- randomized controlled trial
- open label
- papillary thyroid
- prognostic factors
- type diabetes
- multiple sclerosis
- squamous cell carcinoma
- double blind
- systematic review
- bipolar disorder
- adipose tissue
- patient reported
- patient reported outcomes
- combination therapy
- placebo controlled
- preterm birth
- pregnancy outcomes