Gene Expression in Glenoid Articular Cartilage Varies Across Acute Instability, Chronic Instability, and Osteoarthritis.
Alexander W AleemMuhammad Farooq RaiLei CaiRobert H BrophyPublished in: The Journal of bone and joint surgery. American volume (2023)
This exploratory study identified genes of interest, such as CCL3, CHST11, GPR22, PRKAR2B, and PTGS2, that have elevated expression in osteoarthritic glenoid cartilage. These findings provide new biological insight into the relationship between shoulder instability and OA, which could lead to strategies to predict and potentially modify patients' risk of degenerative arthritis due to shoulder instability.
Keyphrases
- gene expression
- rheumatoid arthritis
- end stage renal disease
- newly diagnosed
- ejection fraction
- dna methylation
- drug induced
- liver injury
- poor prognosis
- liver failure
- prognostic factors
- chronic kidney disease
- extracellular matrix
- intensive care unit
- fatty acid
- extracorporeal membrane oxygenation
- liver fibrosis
- binding protein