The Effect of the Long-Term Calcipotriol/Betamethasone Dipropionate Local Therapy on Tissue Resident Memory Cells Markers in Psoriatic Eruptions.
Marta Kasprowicz-FurmańczykJoanna CzerwińskaWaldemar PlacekOwczarczyk-Saczonek AgnieszkaPublished in: International journal of environmental research and public health (2022)
Topical treatment with Cal/BD foam significantly decreased the expression of TRM markers mainly in the epidermis, and to a lesser extent in the dermis, during the 12-week observation period. It probably results from a worse penetration of the drug into the dermis and the effect of the preparation mainly on the epidermis. The persistence of a high expression of TRM markers in the dermis may result in the rapid recurrence of lesions after discontinuation of topical treatment.
Keyphrases
- poor prognosis
- induced apoptosis
- rheumatoid arthritis
- randomized controlled trial
- emergency department
- stem cells
- binding protein
- clinical trial
- cell death
- long non coding rna
- systemic lupus erythematosus
- oxidative stress
- replacement therapy
- high resolution
- study protocol
- quantum dots
- pi k akt
- cell therapy
- sensitive detection
- double blind