Glucocorticoid use in rheumatoid arthritis patients and the onset of pneumonia: a systematic review and meta-analysis.
Kawther N ElsouriVania ArboledaLynn BasbousSamantha HeiserDylon P CollinsPhilip RagusaCourney BaxterDominick CabreraTanisha AkhandEvan StermerKiran SharmaCharmaine SeguroPatrick HardiganMarc KesselmanMichelle Demory BecklerPublished in: Journal of osteopathic medicine (2023)
Our data suggest that RA patients have a higher probability of developing pneumonia on combination therapy with GCs, compared to monotherapy with DMARDs. To our knowledge, our findings are the first to systematically review and statistically evaluate the relationship between the use of GCs and show an increased chance of developing pneumonia.
Keyphrases
- combination therapy
- rheumatoid arthritis patients
- disease activity
- end stage renal disease
- ejection fraction
- rheumatoid arthritis
- newly diagnosed
- healthcare
- peritoneal dialysis
- electronic health record
- prognostic factors
- systemic lupus erythematosus
- community acquired pneumonia
- randomized controlled trial
- ankylosing spondylitis
- machine learning
- big data
- systemic sclerosis
- artificial intelligence
- interstitial lung disease
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- mechanical ventilation