Enhancement of Executive Functions but Not Memory by Multidomain Group Cognitive Training in Patients with Parkinson's Disease and Mild Cognitive Impairment: A Multicenter Randomized Controlled Trial.
Elke KalbeAnn-Kristin FolkertsAnja OpheyCarsten EggersSaskia ElbenKarina DimenshteynPatricia SulzerClaudia SchulteNele SchmidtChristian SchlenstedtDaniela BergKarsten WittLars WojteckiInga Liepelt-ScarfonePublished in: Parkinson's disease (2020)
CT is a safe and feasible therapy option in PD-MCI, yielding executive functions improvement. Data indicate that vulnerable individuals may show the largest cognitive gains. Longitudinal studies are required to determine whether CT may also attenuate cognitive decline in the long term. This trial is registered with DRKS00010186.
Keyphrases
- mild cognitive impairment
- cognitive decline
- randomized controlled trial
- working memory
- study protocol
- image quality
- dual energy
- computed tomography
- contrast enhanced
- cross sectional
- positron emission tomography
- clinical trial
- electronic health record
- phase iii
- big data
- phase ii
- double blind
- mesenchymal stem cells
- systematic review
- virtual reality
- bone marrow
- magnetic resonance
- machine learning
- stem cells