Synthesis and Initial Characterization of a Reversible, Selective 18F-Labeled Radiotracer for Human Butyrylcholinesterase.
Christian GentzschXinyu ChenPhilipp SpatzUrban KošakDamijan KnezNaoko NoseStanislav GobecTakahiro HiguchiMichael DeckerPublished in: Molecular imaging and biology (2021)
The reversibly acting, selective radiotracer is synthetically easily accessible and retains promising activity and binding potential on hBChE. Radiosynthesis with 18F labeling of tosylates was feasible in a reasonable time frame and good radiochemical yield.