Comparison between the cervical and abdominal vagus nerves in mice, pigs, and humans.

Nathalie StakenborgPedro J Gomez-PinillaThomas J M VerlindenAlbert M WolthuisAndre D'HooreRicard FarréPaul HerijgersGianluca MatteoliGuy E Boeckxstaens

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)

The VN composition was largely similar with respect to myelinated and unmyelinated fibers in the species studied. Human and porcine VNs had a comparable diameter and similar amounts of fibrous tissue and contained multiple fascicles, implying that the porcine VN may be suitable to optimize stimulation parameters for clinical trials.

Keyphrases

clinical trial
endothelial cells
induced pluripotent stem cells
high fat diet induced
pluripotent stem cells
type diabetes
randomized controlled trial
phase ii
metabolic syndrome
skeletal muscle
study protocol
open label
genetic diversity
solid state