Effect of altered gene expression in lipid metabolism on cognitive improvement in patients with Alzheimer's dementia following fecal microbiota transplantation: a preliminary study.
Jun-Seob KimHyelim ParkJung-Hwan LeeJongbeom ShinBoram ChaKye Sook KwonYong Woon ShinYerim KimYeoJin KimJong Seok BaeJu-Hun LeeSeok-Jin ChoiTae Jung KimSang-Bae KoSoo-Hyun ParkPublished in: Therapeutic advances in neurological disorders (2024)
These findings suggest a link between alterations in the gut microbiome, gene expression related to lipid metabolism, and cognitive function. The study highlights the importance of gut microbiota in cognitive function and provides insights into potential biomarkers for cognitive decline progression. FMT could complement existing therapies and show potential as a therapeutic intervention to mitigate cognitive decline in AD.