Blood Monocyte Phenotype Fingerprint of Stable Coronary Artery Disease: A Cross-Sectional Substudy of SMARTool Clinical Trial.
Silverio SbranaJonica CampoloAlberto ClementeLuca BastianiAntonella CecchettiniElisa CeccheriniChiara CaselliDanilo NegliaOberdan ParodiDante ChiappinoJeff M SmitArthur J ScholteGualtiero PelosiSilvia RocchiccioliPublished in: BioMed research international (2020)
The results of this study suggest that a specific pattern of inflammation-correlated monocyte marker expression is associated to higher stenosis severity and less calcified lesions in stable CAD. The clinical trial Identifier is NCT04448691.
Keyphrases
- clinical trial
- coronary artery disease
- dendritic cells
- phase ii
- poor prognosis
- endothelial cells
- oxidative stress
- open label
- double blind
- percutaneous coronary intervention
- peripheral blood
- coronary artery bypass grafting
- cardiovascular events
- phase iii
- randomized controlled trial
- heart failure
- binding protein
- immune response
- aortic valve
- cardiovascular disease
- ejection fraction