Effectiveness of Beta-Lactam plus Doxycycline for Patients Hospitalized with Community-Acquired Pneumonia.
Moe UddinTurab MohammedMark MeterskyAntonio AnzuetoCarlos A AlvarezEric M MortensenPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
In this retrospective observational cohort study, we found that doxycycline use, as part of guideline-concordant antibiotic therapy, was associated with lower 30- and 90-day mortality than regimens without doxycycline. While this supports the safety and effectiveness of antibiotic regimes that include doxycycline, additional studies, especially randomized clinical trials, are needed to confirm this.
Keyphrases
- community acquired pneumonia
- end stage renal disease
- randomized controlled trial
- systematic review
- ejection fraction
- chronic kidney disease
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- cross sectional
- type diabetes
- stem cells
- clinical trial
- mesenchymal stem cells
- coronary artery disease
- bone marrow
- multidrug resistant
- cell therapy
- gram negative