Vaccine Effectiveness of JYNNEOS against Mpox Disease in the United States.
Nicholas P DeputyJoseph DeckertAnna N ChardNeil SandbergDanielle L MouliaEric BarkleyAlexandra F DaltonCory SweetAmanda C CohnDavid R LittleAdam L CohenDanessa SandmannDaniel C PayneJacqueline L GerhartLeora R FeldsteinPublished in: The New England journal of medicine (2023)
In this study using nationwide EHR data, patients with mpox were less likely to have received one or two doses of JYNNEOS vaccine than control patients. The findings suggest that JYNNEOS vaccine was effective in preventing mpox disease, and a two-dose series appeared to provide better protection. (Funded by the Centers for Disease Control and Prevention and Epic Research.).