Login / Signup

Effects of temporarily suspending low-dose methotrexate treatment for 2 weeks after SARS-CoV-2 vaccine booster on vaccine response in immunosuppressed adults with inflammatory conditions: protocol for a multicentre randomised controlled trial and nested mechanistic substudy (Vaccine Response On/Off Methotrexate (VROOM) study).

Abhishek AbhishekR J BoytonÁine McKnightLaura CoatesJames BluettVicki S BarberLucy CuretonAnne FrancisDuncan AppelbeLucy EldridgePatrick JulierNicholas PeckhamAna M ValdesInes RombachDaniel M AltmannJonathan Nguyen-Van-TamHywel C WilliamsJonathan Alistair Cook
Published in: BMJ open (2022)
ISRCTN11442263.
Keyphrases
  • low dose
  • sars cov
  • high dose
  • study protocol
  • randomized controlled trial
  • clinical trial
  • oxidative stress
  • respiratory syndrome coronavirus
  • cross sectional
  • coronavirus disease
  • double blind