Oral regimen for high dose methotrexate urine alkalinization: a systematic review and meta-analysis.
Romina Kaveh-AhangaranMohammad AbdollahiMohammad VaeziAmir KasaeianZhalleh BahlouliGhasem JanbabaeeAmirmahdi MojtahedzadehMojtaba MojtahedzadehShirin DjalaliniaBita ShahramiPublished in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2024)
An oral bicarbonate regimen is a safe and effective way to alkalize HDMTX urine, providing a viable and cost-effective alternative to IV protocols. Further prospective multicenter studies are necessary. Systematic review registration identifier: CRD42023379666.