Randomised trial: Peppermint oil (menthol) pharmacokinetics in children and effects on gut motility in children with functional abdominal pain.

Robert J ShulmanBruno P ChumpitaziSusan M Abdel-RahmanUttam GargSalma MusaadGregory L Kearns

Published in: British journal of clinical pharmacology (2021)

Pharmacokinetics and pharmacodynamics of menthol derived from PMO demonstrated apparent dose-proportionality. A higher dose of PMO may be needed to achieve maximal gut response. www.clinicaltrials.gov NCT03295747.

Keyphrases

abdominal pain
young adults
heart rate
randomized controlled trial
open label
study protocol
computed tomography
magnetic resonance imaging
magnetic resonance
escherichia coli
fatty acid
resistance training
staphylococcus aureus
cystic fibrosis
pseudomonas aeruginosa
diffusion weighted imaging
high intensity