Genistein Inhibits C. Difficile Infection via Estrogen Receptors and Lysine Deficient Protein Kinase 1.
Ying XieLindsey FontenotAndrea Chupina EstradaBecca NelsonAshlen BullockKym F FaullHanping FengMingjun SunHon Wai KoonPublished in: The Journal of infectious diseases (2023)
Genistein reduces CDI disease activity by inhibiting pro-inflammatory cytokine expression and apoptosis via the ER/GPER/WNK1 pathways.
Keyphrases
- disease activity
- estrogen receptor
- rheumatoid arthritis
- systemic lupus erythematosus
- protein kinase
- rheumatoid arthritis patients
- ankylosing spondylitis
- poor prognosis
- juvenile idiopathic arthritis
- oxidative stress
- endoplasmic reticulum stress
- cell cycle arrest
- cell death
- binding protein
- breast cancer cells
- endoplasmic reticulum