Laparoscopic Versus Open Hemihepatectomy: The ORANGE II PLUS Multicenter Randomized Controlled Trial.
Robert S FichtingerLuca A AldrighettiMohammed Abu HilalRoberto Ivan TroisiRobert Peter SutcliffeMarc G H BesselinkSomaiah ArooriKrishna V MenonBjørn EdwinMathieu D'HondtValerio LucidiTom F UlmerRafael Díaz-NietoZahir SoonawallaSteve WhiteGregory SergeantBram OlijFrancesca RattiChristoph KuemmerliVincenzo ScuderiFrederik BerrevoetAude VanlanderRavi MarudanayagamPieter J TanisMaxime J L DewulfCornelis H C DejongZina EmintonMerel L KimmanLloyd BrandtsUlf Peter NeumannÅsmund Avdem FretlandSiân A PughGerard J P van BreukelenJohn N PrimroseRonald M van Damnull nullPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Among patients undergoing hemihepatectomy, the laparoscopic approach resulted in a shorter time to functional recovery compared with open surgery. In addition, it was associated with a better QoL, and in patients with cancer, a shorter time to adjuvant systemic therapy with no adverse impact on cancer outcomes observed.
Keyphrases
- minimally invasive
- robot assisted
- randomized controlled trial
- patients undergoing
- papillary thyroid
- study protocol
- early stage
- coronary artery bypass
- squamous cell
- cross sectional
- double blind
- surgical site infection
- type diabetes
- emergency department
- mesenchymal stem cells
- lymph node metastasis
- clinical trial
- adipose tissue
- acute coronary syndrome
- young adults
- percutaneous coronary intervention
- cell therapy
- insulin resistance
- adverse drug
- weight loss
- bone marrow