Investigating the Safety and Efficacy of Therapeutic Hypothermia in Pediatric Severe Traumatic Brain Injury: A Systematic Review and Meta-Analysis.
Seyed Ahmad Naseri AlaviMohammad Amin HabibiAlireza MajdiBardia HajikarimlooFarhang RashidiSahar Fathi TavaniPoriya MinaeeSeyed Mohammad EaziAndrew J KobetsPublished in: Children (Basel, Switzerland) (2024)
Our findings challenge the effectiveness of therapeutic hypothermia in pediatric TBI cases. Despite expectations, it did not significantly improve key clinical outcomes. This prompts a critical re-evaluation of hypothermia's role as a standard intervention in pediatric TBI treatment.