Comparison of MRI Lesion Evolution in Different Central Nervous System Demyelinating Disorders.
Elia SechiKarl N KreckeSteven A MessinaMarina BuciucSean J PittockJohn J ChenBrian G WeinshenkerA Sebastian Lopez-ChiribogaClaudia F LucchinettiNicholas L ZalewskiJan Mendelt TillemaAmy KunchokSalvatore MonacoPadraig P MorrisJames P FryerAdam NguyenTammy GreenwoodStephanie B Syc-MazurekB Mark KeeganEoin Patrick FlanaganPublished in: Neurology (2021)
The MRI T2 lesions in MOGAD resolve completely more often than in AQP4-IgG-NMOSD and MS. This has implications for diagnosis, monitoring disease activity, and clinical trial design, while also providing insight into pathogenesis of CNS demyelinating diseases.
Keyphrases
- disease activity
- rheumatoid arthritis
- systemic lupus erythematosus
- clinical trial
- contrast enhanced
- rheumatoid arthritis patients
- magnetic resonance imaging
- ankylosing spondylitis
- diffusion weighted imaging
- juvenile idiopathic arthritis
- multiple sclerosis
- mass spectrometry
- blood brain barrier
- ms ms
- computed tomography
- randomized controlled trial
- magnetic resonance
- phase ii
- study protocol
- cerebrospinal fluid