Nearly Complete Genome Sequence of Brugia malayi Strain FR3.

Alan TraceyJeremy M FosterMichael PauliniAlexandra GroteJohn MattickYu-Chih TsaiMatthew ChungJames A CottonTyson A ClarkAdam GeberNancy HolroydJonas KorlachSilvia LibroSara LustigmanMichelle L MichalskiMatthew B RogersAlan TwaddleJulie C Dunning HotoppMatthew BerrimanElodie Ghedin

Published in: Microbiology resource announcements (2020)

Lymphatic filariasis affects ∼120 million people and can result in elephantiasis and hydrocele. Here, we report the nearly complete genome sequence of the best-studied causative agent of lymphatic filariasis, Brugia malayi The assembly contains four autosomes, an X chromosome, and only eight gaps but lacks a contiguous sequence for the known Y chromosome.

Keyphrases

lymph node
copy number
dna methylation
gene expression
amino acid
drug administration