Effect of methotrexate use on the development of type 2 diabetes in rheumatoid arthritis patients: A systematic review and meta-analysis.
Leena Rashad BaghdadiPublished in: PloS one (2020)
Rheumatoid arthritis patients on methotrexate treatment had a lower risk of developing type 2 diabetes compared to rheumatoid arthritis patients not exposed to methotrexate. This finding highlights the need for future, randomized control trials to confirm the beneficial effect of methotrexate on type 2 diabetes in the rheumatoid arthritis population.
Keyphrases
- rheumatoid arthritis patients
- type diabetes
- disease activity
- rheumatoid arthritis
- high dose
- systemic lupus erythematosus
- glycemic control
- ankylosing spondylitis
- cardiovascular disease
- insulin resistance
- randomized controlled trial
- double blind
- interstitial lung disease
- current status
- metabolic syndrome
- idiopathic pulmonary fibrosis
- placebo controlled