APOBEC3F is a mutational driver of the human Monkeypox virus identified in the 2022 outbreak.
Rodolphe SuspèneKyle A RaymondLaetitia BoutinSophie GuillierFrederic LemoineOlivier FerrarisJean-Nicolas TournierFrédéric IseniEtienne Simon-LorièreJean-Pierre VartanianPublished in: The Journal of infectious diseases (2023)
Stochastic or transient overexpression of APOBEC3F gene exposes the MPXV genome to a broad spectrum of mutations that may be modeling the mutational landscape after multiple cycles of viral replication.