Thyroidectomy for Euthyroid Patients with Hashimoto Disease and Persistent Symptoms: An Observational, Postrandomization Study.
Geir HoffTomm BernklevLene JohnsenLaurens ReitsmaDirk SinaAndromeda LauzikeCharlotte GibbsTone Hoel LendeJon Kristian NarvestadRasmus KildahlRoald OmdalJan Terje KvaløyHåvard SøilandPublished in: Journal of thyroid research (2024)
Thyroidectomy had a beneficial symptom-reducing effect in euthyroid patients with Hashimoto disease and persistent symptoms. The pathophysiology of residual symptoms remains unclear, and surgical complication rates are high. If thyroidectomy is considered as a treatment option, it should be performed in dedicated centers with experienced endocrine surgeons and as part of further studies on persistent symptoms. This trial is registered with NCT-02319538.