Clinicopathological Impact of FOXM1 and MMP-9 Immunohistochemical Expression in Different Grades of Intracranial Meningioma.

Hanaa M IbrahimAziza E AbdelrahmanAmira ElwanShimaa A GhariebMohammed RefaatWael ElmesallamyAmira A Salem

Published in: Applied immunohistochemistry & molecular morphology : AIMM (2024)

Strong FOXM1, strong MMP-9, and high Ki67 in meningiomas indicate highly aggressive tumors with a shortened survival rate, dismal outcome, and high risk of recurrence after the standard protocol of therapy.

Keyphrases

poor prognosis
randomized controlled trial
optic nerve
neoadjuvant chemotherapy
stem cells
radiation therapy
bone marrow
cell therapy