Collagen Remodeling and Fatty Acid Regulation Biomarkers in Understanding the Molecular Pathogenesis of Atrial Fibrillation.
Ameer OdehGabriel D DunganAmir DarkiDebra Moorman HoppensteadtFakiha SiddiquiBulent KantarciogluJawed FareedMushabbar A SyedPublished in: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis (2022)
The elevation of collagen remodeling biomarkers suggests an upregulation of these biomarkers and their potential role in AF, which may contribute to atrial fibrosis. L-FABP and NEFAs were elevated in AF patients. The correlations between the collagen remodeling and fatty acid dysregulation biomarkers may be due to their involvement in structural remodeling of the atria.
Keyphrases
- atrial fibrillation
- fatty acid
- end stage renal disease
- catheter ablation
- chronic kidney disease
- left atrial
- ejection fraction
- newly diagnosed
- heart failure
- peritoneal dialysis
- cell proliferation
- wound healing
- left atrial appendage
- poor prognosis
- tissue engineering
- percutaneous coronary intervention
- binding protein
- acute coronary syndrome
- long non coding rna