Lifestyle Intervention Improves Prothrombotic Coagulation Profile in Individuals at High Risk for Type 2 Diabetes.

Sebastian HörberRainer LehmannLouise FritscheJuergen MachannAndreas L BirkenfeldHans-Ulrich HäringNorbert Stefan Martin HeniAndreas FritscheAndreas Peter

Published in: The Journal of clinical endocrinology and metabolism (2021)

Lifestyle intervention is able to improve a prothrombotic state in individuals at high risk for type 2 diabetes. Besides body weight, liver fat content, insulin sensitivity, and systemic low-grade inflammation are potential mechanisms for improvements in hemostasis and could represent future therapeutic targets.

Keyphrases

low grade
type diabetes
body weight
cardiovascular disease
randomized controlled trial
high grade
metabolic syndrome
glycemic control
weight loss
physical activity
oxidative stress
insulin resistance
adipose tissue
fatty acid
risk assessment