Robert Letsinger and the Evolution of Oligonucleotide Synthesis.

This retrospective summarizes a presentation given at the symposium "Bob Letsinger, PhD-100 Years of History" on September 28, 2021 as part of the 17th annual meeting of the Oligonucleotide Therapeutics Society (OTS). In it I look back at my encounters with Robert Lewis Letsinger (1921-2014) while at Northwestern University as Assistant Professor between 1995 and 2000.